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FAM209A family with sequence similarity 209 member A [ Homo sapiens (human) ]

Gene ID: 200232, updated on 28-Jan-2023

Summary

Official Symbol
FAM209Aprovided by HGNC
Official Full Name
family with sequence similarity 209 member Aprovided by HGNC
Primary source
HGNC:HGNC:16100
See related
Ensembl:ENSG00000124103 AllianceGenome:HGNC:16100
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C20orf106; dJ1153D9.3
Summary
Located in extracellular exosome and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 36.8) See more
Orthologs
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Genomic context

See FAM209A in Genome Data Viewer
Location:
20q13.31
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (56524744..56533590)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (58302238..58303646)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (55099800..55101208)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene Cas scaffold protein family member 4 Neighboring gene ribosomal protein L39 pseudogene Neighboring gene small nucleolar RNA U13 Neighboring gene replication termination factor 2 Neighboring gene glucosaminyl (N-acetyl) transferase family member 7 Neighboring gene family with sequence similarity 209 member B Neighboring gene uncharacterized LOC124904971 Neighboring gene long intergenic non-protein coding RNA 1716

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC104272

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
located_in nuclear inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus HDA PubMed 

General protein information

Preferred Names
protein FAM209A
Names
uncharacterized protein C20orf106

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012971.4NP_001012989.2  protein FAM209A precursor

    See identical proteins and their annotated locations for NP_001012989.2

    Status: VALIDATED

    Source sequence(s)
    AL109806
    Consensus CDS
    CCDS33493.1
    UniProtKB/Swiss-Prot
    Q05C43, Q5JX71
    Related
    ENSP00000360379.4, ENST00000371328.5
    Conserved Domains (1) summary
    pfam15206
    Location:20168
    FAM209; FAM209 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    56524744..56533590
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047439965.1XP_047295921.1  protein FAM209A isoform X1

    UniProtKB/Swiss-Prot
    Q05C43
  2. XM_047439964.1XP_047295920.1  protein FAM209A isoform X1

    UniProtKB/Swiss-Prot
    Q05C43

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    58302238..58303646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)