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Mrpl23 mitochondrial ribosomal protein L23 [ Mus musculus (house mouse) ]

Gene ID: 19935, updated on 1-Mar-2024

Summary

Official Symbol
Mrpl23provided by MGI
Official Full Name
mitochondrial ribosomal protein L23provided by MGI
Primary source
MGI:MGI:1196612
See related
Ensembl:ENSMUSG00000037772 AllianceGenome:MGI:1196612
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpl23; L23mrp; Rpl23l
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to act upstream of or within translation. Located in mitochondrial ribosome. Is expressed in several structures, including early conceptus; forelimb bud; genitourinary system; liver; and thymus primordium. Orthologous to human MRPL23 (mitochondrial ribosomal protein L23). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 15.3), bladder adult (RPKM 14.9) and 28 other tissues See more
Orthologs
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Genomic context

See Mrpl23 in Genome Data Viewer
Location:
7 F5; 7 87.95 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (142086423..142094484)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (142532467..142540747)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10483 Neighboring gene lymphocyte specific 1 Neighboring gene proline rich 33 Neighboring gene troponin T3, skeletal, fast Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:149724284-149724471 Neighboring gene H19/Igf2 enhancer region Neighboring gene non-coding transcript 1 Neighboring gene microRNA 675 Neighboring gene H19, imprinted maternally expressed transcript

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (4) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in mitochondrial translation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within translation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in mitochondrial ribosome IDA
Inferred from Direct Assay
more info
 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
large ribosomal subunit protein uL23m
Names
39S ribosomal protein L23, mitochondrial
L23 mitochondrial-related protein
L23mt
MRP-L23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001417208.1NP_001404137.1  large ribosomal subunit protein uL23m isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC013548, AL603651
    UniProtKB/TrEMBL
    A0A1B0GSZ9
    Related
    ENSMUST00000137345.9
  2. NM_001417209.1NP_001404138.1  large ribosomal subunit protein uL23m isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC013548, AL603651
    UniProtKB/TrEMBL
    A0A1B0GSZ9
  3. NM_001417210.1NP_001404139.1  large ribosomal subunit protein uL23m isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC013548, AL603651
  4. NM_001417211.1NP_001404140.1  large ribosomal subunit protein uL23m isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC013548, AL603651
    UniProtKB/TrEMBL
    A0A1B0GQZ1
    Related
    ENSMUSP00000147311.2, ENSMUST00000210803.2
  5. NM_011288.3NP_035418.1  large ribosomal subunit protein uL23m isoform 2

    See identical proteins and their annotated locations for NP_035418.1

    Status: VALIDATED

    Source sequence(s)
    AC013548, AL603651
    Consensus CDS
    CCDS22032.1
    UniProtKB/Swiss-Prot
    O35972, Q78E46
    UniProtKB/TrEMBL
    A0A1B0GSZ9
    Related
    ENSMUSP00000039784.7, ENSMUST00000038675.7
    Conserved Domains (1) summary
    pfam00276
    Location:42105
    Ribosomal_L23; Ribosomal protein L23

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    142086423..142094484
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006508516.5XP_006508579.1  large ribosomal subunit protein uL23m isoform X2

    UniProtKB/TrEMBL
    A0A1B0GSZ9
    Related
    ENSMUSP00000148138.2, ENSMUST00000210662.2
    Conserved Domains (1) summary
    pfam00276
    Location:40105
    Ribosomal_L23; Ribosomal protein L23