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Lrrc75a leucine rich repeat containing 75A [ Mus musculus (house mouse) ]

Gene ID: 192976, updated on 5-Mar-2024


Official Symbol
Lrrc75aprovided by MGI
Official Full Name
leucine rich repeat containing 75Aprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000046417 AllianceGenome:MGI:2682293
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Predicted to be active in cytoplasm. Orthologous to human LRRC75A (leucine rich repeat containing 75A). [provided by Alliance of Genome Resources, Apr 2022]
Broad expression in colon adult (RPKM 21.1), duodenum adult (RPKM 20.6) and 23 other tissues See more
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Genomic context

See Lrrc75a in Genome Data Viewer
11 B2; 11 38.51 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (62495708..62539411, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (62604884..62648523, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2410006H16 gene Neighboring gene small nucleolar RNA, C/D box 49A Neighboring gene small nucleolar RNA, C/D box 65 Neighboring gene leucine rich repeat containing 75A, opposite strand 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:62462281-62462390 Neighboring gene membrane magnesium transporter 2 Neighboring gene zinc finger protein 287 Neighboring gene nuclear encoded tRNA trytophan 8 (anticodon CCA)

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Clone Names

  • MGC59632

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info

General protein information

Preferred Names
leucine-rich repeat-containing protein 75A
family with sequence similarity 211, member A
leucine-rich repeat-containing protein C17orf76 homolog
leucine-rich repeat-containing protein FAM211A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357955.1NP_001344884.1  leucine-rich repeat-containing protein 75A isoform 2

    Status: VALIDATED

    Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region and initiates translation from a downstream start codon, compared to variant 1. It encodes isoform 2, which is shorter at the N-terminus, compared to isoform 1.
    Source sequence(s)
    AK146714, BC053455, BY238469
    Conserved Domains (1) summary
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
  2. NM_198861.1NP_942561.1  leucine-rich repeat-containing protein 75A isoform 1

    See identical proteins and their annotated locations for NP_942561.1

    Status: VALIDATED

    Transcript Variant: This variant 1 represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    Consensus CDS
    Q3UIX7, Q7TSF4, Q811G5
    ENSMUSP00000062489.9, ENSMUST00000057194.9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000077.7 Reference GRCm39 C57BL/6J

    62495708..62539411 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156450.1XP_036012343.1  leucine-rich repeat-containing protein 75A isoform X2

  2. XM_036156449.1XP_036012342.1  leucine-rich repeat-containing protein 75A isoform X1