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Psmb6 proteasome (prosome, macropain) subunit, beta type 6 [ Mus musculus (house mouse) ]

Gene ID: 19175, updated on 8-Jul-2018
Official Symbol
Psmb6provided by MGI
Official Full Name
proteasome (prosome, macropain) subunit, beta type 6provided by MGI
Primary source
MGI:MGI:104880
See related
Ensembl:ENSMUSG00000018286 Vega:OTTMUSG00000006054
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mpnd; Lmp19
Expression
Ubiquitous expression in large intestine adult (RPKM 110.6), testis adult (RPKM 105.7) and 28 other tissues See more
Orthologs
See Psmb6 in Genome Data Viewer
Location:
11 B3; 11 42.99 cM
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (70525357..70527858)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (70338859..70341360)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene vitelline membrane outer layer 1 homolog (chicken) Neighboring gene glycolipid transfer protein domain containing 2 Neighboring gene predicted gene, 40193 Neighboring gene phospholipase D2

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
threonine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
proteasomal protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasomal ubiquitin-independent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
proteolysis involved in cellular protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
proteasome complex ISO
Inferred from Sequence Orthology
more info
 
proteasome core complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome core complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
proteasome subunit beta type-6
Names
low molecular mass protein 19
macropain delta chain
multicatalytic endopeptidase complex delta chain
proteasome delta chain
proteasome subunit Y
subunit 2
NP_032972.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008946.4NP_032972.3  proteasome subunit beta type-6 precursor

    See identical proteins and their annotated locations for NP_032972.3

    Status: VALIDATED

    Source sequence(s)
    AK167227, AV072442, BM202854, BY069663
    Consensus CDS
    CCDS48836.1
    UniProtKB/Swiss-Prot
    Q60692
    Related
    ENSMUSP00000018430.6, OTTMUSP00000006323, ENSMUST00000018430.6, OTTMUST00000013639
    Conserved Domains (2) summary
    TIGR03690
    Location:33219
    20S_bact_beta; proteasome, beta subunit, bacterial type
    cd03762
    Location:34221
    proteasome_beta_type_6; proteasome beta type-6 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

    Range
    70525357..70527858
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p4 NOD/MrkTac

Genomic

  1. NT_187026.1 Reference GRCm38.p4 NOD/MrkTac

    Range
    629820..632320
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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