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Psma2 proteasome (prosome, macropain) subunit, alpha type 2 [ Mus musculus (house mouse) ]

Gene ID: 19166, updated on 3-Jun-2018
Official Symbol
Psma2provided by MGI
Official Full Name
proteasome (prosome, macropain) subunit, alpha type 2provided by MGI
Primary source
MGI:MGI:104885
See related
Ensembl:ENSMUSG00000015671
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lmpc3
Expression
Ubiquitous expression in placenta adult (RPKM 107.2), liver E14 (RPKM 90.2) and 28 other tissues See more
Orthologs
See Psma2 in Genome Data Viewer
Location:
13; 13 A1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (14613242..14625673)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (14705509..14717940)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 32526 Neighboring gene mitochondrial ribosomal protein L32 Neighboring gene expressed sequence AW209491 Neighboring gene guanine nucleotide binding protein (G protein), alpha inhibiting 3 pseudogene

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
threonine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
proteasomal protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasomal ubiquitin-independent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
proteolysis involved in cellular protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
P-body IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
proteasome complex ISO
Inferred from Sequence Orthology
more info
 
proteasome core complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome core complex IDA
Inferred from Direct Assay
more info
PubMed 
proteasome core complex, alpha-subunit complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome core complex, alpha-subunit complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
proteasome subunit alpha type-2
Names
macropain subunit C3
multicatalytic endopeptidase complex subunit C3
proteasome component C3
NP_032970.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008944.2NP_032970.2  proteasome subunit alpha type-2

    See identical proteins and their annotated locations for NP_032970.2

    Status: VALIDATED

    Source sequence(s)
    AK152862, BU755659, CJ052982
    Consensus CDS
    CCDS36602.1
    UniProtKB/Swiss-Prot
    P49722
    Related
    ENSMUSP00000129767.2, ENSMUST00000170836.3
    Conserved Domains (1) summary
    cd03750
    Location:6231
    proteasome_alpha_type_2; proteasome_alpha_type_2. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

    Range
    14613242..14625673
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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