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Pgk2 phosphoglycerate kinase 2 [ Mus musculus (house mouse) ]

Gene ID: 18663, updated on 8-Feb-2024

Summary

Official Symbol
Pgk2provided by MGI
Official Full Name
phosphoglycerate kinase 2provided by MGI
Primary source
MGI:MGI:97563
See related
Ensembl:ENSMUSG00000031233 AllianceGenome:MGI:97563
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pgk-2; Tcp-2
Summary
Enables phosphoglycerate kinase activity. Acts upstream of or within flagellated sperm motility and glycolytic process. Located in sperm fibrous sheath. Is expressed in germ cell of testis and testis. Orthologous to human PGK2 (phosphoglycerate kinase 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See Pgk2 in Genome Data Viewer
Location:
17 B2; 17 19.44 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (40517909..40519500, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (40207018..40208609, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene exocrine gland secreted peptide 38 Neighboring gene TGFB-induced factor homeobox 2, pseudogene 2 Neighboring gene STARR-seq mESC enhancer starr_42539 Neighboring gene cysteine-rich secretory protein 3 Neighboring gene cysteine-rich secretory protein 1

Genomic regions, transcripts, and products

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ADP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphoglycerate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphoglycerate kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphoglycerate kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables phosphoglycerate kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within flagellated sperm motility IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in gluconeogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in glycolytic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within glycolytic process IC
Inferred by Curator
more info
PubMed 
acts_upstream_of_or_within glycolytic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cilium IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in sperm fibrous sheath IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in sperm fibrous sheath IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
phosphoglycerate kinase 2
Names
phosphoglycerate kinase, testis specific
NP_112467.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031190.2NP_112467.2  phosphoglycerate kinase 2

    See identical proteins and their annotated locations for NP_112467.2

    Status: VALIDATED

    Source sequence(s)
    BC061054, BU937018
    Consensus CDS
    CCDS28782.1
    UniProtKB/Swiss-Prot
    P09041, Q5RKV3, Q6P8V2
    Related
    ENSMUSP00000033585.5, ENSMUST00000033585.7
    Conserved Domains (1) summary
    PTZ00005
    Location:3416
    PTZ00005; phosphoglycerate kinase; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    40517909..40519500 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)