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mt-Tl1 tRNA leucine 1, mitochondrial [ Mus musculus (house mouse) ]

Gene ID: 17735, updated on 11-Apr-2024

Summary

Official Symbol
mt-Tl1provided by MGI
Official Full Name
tRNA leucine 1, mitochondrialprovided by MGI
Primary source
MGI:MGI:102482
See related
AllianceGenome:MGI:102482
Gene type
tRNA
Organism
Mus musculus (strain: C57BL/6J)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TrnL1
Summary
Predicted to enable triplet codon-amino acid adaptor activity. Predicted to act upstream of or within translation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in cardiomyopathy. Orthologous to human MT-TL1 (mitochondrially encoded tRNA-Leu (UUA/G) 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) MT (non-nuclear) NC_005089.1 (2676..2750)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) MT (non-nuclear) NC_005089.1 (2676..2750)

Chromosome MT - NC_005089.1Genomic Context describing neighboring genes Neighboring gene 16S ribosomal RNA Neighboring gene tRNA-Val Neighboring gene NADH dehydrogenase subunit 1 Neighboring gene tRNA-Ile Neighboring gene tRNA-Gln

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

  • tRNA-Leu_1

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables triplet codon-amino acid adaptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within translation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
acts_upstream_of_or_within translational elongation TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrion TAS
Traceable Author Statement
more info
PubMed