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Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) [ Mus musculus (house mouse) ]

Gene ID: 17133, updated on 25-Nov-2021

Summary

Official Symbol
Maffprovided by MGI
Official Full Name
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)provided by MGI
Primary source
MGI:MGI:96910
See related
Ensembl:ENSMUSG00000042622
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Broad expression in small intestine adult (RPKM 12.2), duodenum adult (RPKM 12.0) and 23 other tissues See more
Orthologs
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Genomic context

See Maff in Genome Data Viewer
Location:
15 E1; 15 37.7 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (79230821..79243278)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (79346621..79359078)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (79178108..79189506)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene phospholipase A2, group VI Neighboring gene predicted gene, 41358 Neighboring gene predicted gene 20420 Neighboring gene transmembrane protein 184b Neighboring gene microRNA 1943 Neighboring gene casein kinase 1, epsilon Neighboring gene predicted gene 16059

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transcription factor MafF
Names
V-maf musculoaponeurotic fibrosarcoma oncogene homolog F

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304830.1NP_001291759.1  transcription factor MafF isoform 1

    See identical proteins and their annotated locations for NP_001291759.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein (isoform 1).
    Source sequence(s)
    AK146043, BX515677
    Consensus CDS
    CCDS27638.1
    UniProtKB/Swiss-Prot
    O54791
    UniProtKB/TrEMBL
    Q3U0G5
    Related
    ENSMUSP00000154850.2, ENSMUST00000229130.2
    Conserved Domains (1) summary
    cd14717
    Location:47115
    bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
  2. NM_001304831.1NP_001291760.1  transcription factor MafF isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate exon in the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    AC165278
    UniProtKB/TrEMBL
    A0A1S6GWH7
    Conserved Domains (1) summary
    cd14717
    Location:75143
    bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
  3. NM_001304832.1NP_001291761.1  transcription factor MafF isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) contains an alternate exon in the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    AC165278
    Conserved Domains (1) summary
    cd14717
    Location:66134
    bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
  4. NM_010755.4NP_034885.1  transcription factor MafF isoform 1

    See identical proteins and their annotated locations for NP_034885.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the shortest isoform (1). Both variants 1 and 2 encode the same protein (isoform 1).
    Source sequence(s)
    AK146043, BX515677, CX211309
    Consensus CDS
    CCDS27638.1
    UniProtKB/Swiss-Prot
    O54791
    UniProtKB/TrEMBL
    Q3U0G5
    Related
    ENSMUSP00000094076.4, ENSMUST00000096350.11
    Conserved Domains (1) summary
    cd14717
    Location:47115
    bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    79230821..79243278
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159212.1XP_036015105.1  transcription factor MafF isoform X1

    Conserved Domains (1) summary
    cd14717
    Location:158226
    bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
  2. XM_036159213.1XP_036015106.1  transcription factor MafF isoform X2

    Conserved Domains (1) summary
    cd14717
    Location:47115
    bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
  3. XM_006520550.5XP_006520613.1  transcription factor MafF isoform X2

    See identical proteins and their annotated locations for XP_006520613.1

    UniProtKB/Swiss-Prot
    O54791
    UniProtKB/TrEMBL
    Q3U0G5
    Conserved Domains (1) summary
    cd14717
    Location:47115
    bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
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