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GALNTL5 polypeptide N-acetylgalactosaminyltransferase like 5 [ Homo sapiens (human) ]

Gene ID: 168391, updated on 17-Jun-2019

Summary

Official Symbol
GALNTL5provided by HGNC
Official Full Name
polypeptide N-acetylgalactosaminyltransferase like 5provided by HGNC
Primary source
HGNC:HGNC:21725
See related
Ensembl:ENSG00000106648 MIM:615133
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GALNT15; GALNACT19; GalNAc-T5L
Expression
Restricted expression toward testis (RPKM 6.9) See more
Orthologs

Genomic context

See GALNTL5 in Genome Data Viewer
Location:
7q36.1
Exon count:
16
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (151956379..152019934)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (151653464..151717019)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375570 Neighboring gene uncharacterized LOC105375571 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 11 Neighboring gene uncharacterized LOC731075 Neighboring gene Y-box binding protein 1 pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
NOT transferase activity, transferring glycosyl groups IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
NOT protein glycosylation IDA
Inferred from Direct Assay
more info
PubMed 
spermatid development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spermatid development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
late endosome membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5
Names
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
galNAc-T15
polypeptide GalNAc transferase 15
polypeptide GalNAc transferase-like 5
pp-GaNTase 15
protein-UDP acetylgalactosaminyltransferase 15
putative polypeptide N-acetylgalactosaminyltransferase-like protein 5
testis tissue sperm-binding protein Li 61n
NP_660335.2
XP_006715925.1
XP_011514151.1
XP_011514154.1
XP_011514155.1
XP_016867282.1
XP_016867283.1
XP_016867284.1
XP_016867285.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145292.4NP_660335.2  inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5

    See identical proteins and their annotated locations for NP_660335.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the functional protein.
    Source sequence(s)
    AC074257, AW103179, BC022021
    Consensus CDS
    CCDS5929.1
    UniProtKB/Swiss-Prot
    Q7Z4T8
    Related
    ENSP00000376548.2, ENST00000392800.7
    Conserved Domains (2) summary
    cd02510
    Location:137433
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    COG1216
    Location:134384
    GT2; Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism]

RNA

  1. NR_033169.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR and uses an alternate splice site in an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC074257, AK315667, AW103179, DB022678
    Related
    ENST00000426341.6

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    151956379..152019934
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006715862.4XP_006715925.1  inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 isoform X2

    See identical proteins and their annotated locations for XP_006715925.1

    UniProtKB/Swiss-Prot
    Q7Z4T8
    Related
    ENSP00000479207.1, ENST00000616416.4
    Conserved Domains (2) summary
    cd02510
    Location:137433
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    COG1216
    Location:134384
    GT2; Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism]
  2. XM_017011796.1XP_016867285.1  inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 isoform X7

  3. XM_017011795.1XP_016867284.1  inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 isoform X6

  4. XM_017011793.2XP_016867282.1  inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 isoform X1

    Conserved Domains (2) summary
    cd02510
    Location:190486
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    COG1216
    Location:187437
    GT2; Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism]
  5. XM_017011794.1XP_016867283.1  inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 isoform X5

  6. XM_011515849.3XP_011514151.1  inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 isoform X3

    Conserved Domains (2) summary
    cd02510
    Location:64360
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    COG1215
    Location:57285
    BcsA; Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility]
  7. XM_011515852.2XP_011514154.1  inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 isoform X4

    See identical proteins and their annotated locations for XP_011514154.1

    Conserved Domains (2) summary
    cd02510
    Location:26322
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    COG1215
    Location:19247
    BcsA; Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility]
  8. XM_011515853.2XP_011514155.1  inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 isoform X4

    See identical proteins and their annotated locations for XP_011514155.1

    Conserved Domains (2) summary
    cd02510
    Location:26322
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    COG1215
    Location:19247
    BcsA; Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility]

RNA

  1. XR_001744572.1 RNA Sequence

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