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TIGD2 tigger transposable element derived 2 [ Homo sapiens (human) ]

Gene ID: 166815, updated on 23-Nov-2021

Summary

Official Symbol
TIGD2provided by HGNC
Official Full Name
tigger transposable element derived 2provided by HGNC
Primary source
HGNC:HGNC:18333
See related
Ensembl:ENSG00000180346 MIM:612973
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HEL106
Summary
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See TIGD2 in Genome Data Viewer
Location:
4q22.1
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (89111169..89114901)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (90032320..90036052)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene HNF1 motif-containing MPRA enhancer 87 Neighboring gene family with sequence similarity 13 member A Neighboring gene uncharacterized LOC105377327 Neighboring gene RNA, U6 small nuclear 907, pseudogene Neighboring gene GPRIN family member 3

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp667D1322

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
tigger transposable element-derived protein 2
Names
epididymis luminal protein 106

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001382380.1NP_001369309.1  tigger transposable element-derived protein 2

    Status: REVIEWED

    Source sequence(s)
    AC104785
    Related
    ENSP00000317170.2, ENST00000317005.2
    Conserved Domains (3) summary
    pfam03184
    Location:207385
    DDE_1; DDE superfamily endonuclease
    pfam03221
    Location:76135
    HTH_Tnp_Tc5; Tc5 transposase DNA-binding domain
    cl21459
    Location:452
    HTH; Helix-turn-helix domains
  2. NM_145715.3NP_663761.1  tigger transposable element-derived protein 2

    See identical proteins and their annotated locations for NP_663761.1

    Status: REVIEWED

    Source sequence(s)
    AC104785
    Consensus CDS
    CCDS3633.1
    UniProtKB/Swiss-Prot
    Q4W5G0
    UniProtKB/TrEMBL
    B3KNK0, V9HWD1
    Related
    ENSP00000486687.1, ENST00000603357.3
    Conserved Domains (3) summary
    pfam03184
    Location:207385
    DDE_1; DDE superfamily endonuclease
    pfam03221
    Location:76135
    HTH_Tnp_Tc5; Tc5 transposase DNA-binding domain
    cl21459
    Location:452
    HTH; Helix-turn-helix domains

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    89111169..89114901
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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