Format

Send to:

Choose Destination

GPR156 G protein-coupled receptor 156 [ Homo sapiens (human) ]

Gene ID: 165829, updated on 23-Nov-2021

Summary

Official Symbol
GPR156provided by HGNC
Official Full Name
G protein-coupled receptor 156provided by HGNC
Primary source
HGNC:HGNC:20844
See related
Ensembl:ENSG00000175697 MIM:610464
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PGR28; GABABL
Summary
G protein-coupled receptors (GPCRs) are a large superfamily of cell surface receptors characterized by 7 helical transmembrane domains, together with N-terminal extracellular and C-terminal intracellular domains.[supplied by OMIM, Mar 2008]
Expression
Biased expression in testis (RPKM 1.8), ovary (RPKM 0.3) and 7 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See GPR156 in Genome Data Viewer
Location:
3q13.33
Exon count:
15
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (120165478..120285222, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (119884325..120004069, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 762, pseudogene Neighboring gene RNA, 7SL, cytoplasmic 397, pseudogene Neighboring gene uncharacterized LOC105374065 Neighboring gene PTOV1, extended AT-hook containing adaptor protein pseudogene Neighboring gene leucine rich repeat containing 58

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC142261

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled GABA receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transmembrane signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in gamma-aminobutyric acid signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of G protein-coupled receptor heterodimeric complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
probable G-protein coupled receptor 156
Names
G protein-coupled receptor PGR28
GABAB-related G-protein coupled receptor

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168271.2NP_001161743.1  probable G-protein coupled receptor 156 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AC063952, AC092897, AI201720, BC143606, BX115336, CD638213
    Consensus CDS
    CCDS54629.1
    UniProtKB/Swiss-Prot
    Q8NFN8
    Related
    ENSP00000418758.1, ENST00000461057.1
    Conserved Domains (1) summary
    pfam00003
    Location:71308
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
  2. NM_153002.3NP_694547.2  probable G-protein coupled receptor 156 isoform 1

    See identical proteins and their annotated locations for NP_694547.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC063952, AC092897, AF488739, AI201720, BX115336, CD638213
    Consensus CDS
    CCDS2997.1
    UniProtKB/Swiss-Prot
    Q8NFN8
    Related
    ENSP00000417261.1, ENST00000464295.6
    Conserved Domains (1) summary
    pfam00003
    Location:71312
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    120165478..120285222 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011512484.3XP_011510786.1  probable G-protein coupled receptor 156 isoform X3

    See identical proteins and their annotated locations for XP_011510786.1

    Conserved Domains (1) summary
    pfam00003
    Location:1231
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
  2. XM_017005796.1XP_016861285.1  probable G-protein coupled receptor 156 isoform X1

    UniProtKB/Swiss-Prot
    Q8NFN8
    Conserved Domains (1) summary
    pfam00003
    Location:71312
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
  3. XM_017005795.1XP_016861284.1  probable G-protein coupled receptor 156 isoform X1

    UniProtKB/Swiss-Prot
    Q8NFN8
    Conserved Domains (1) summary
    pfam00003
    Location:71312
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
  4. XM_011512487.1XP_011510789.1  probable G-protein coupled receptor 156 isoform X3

    See identical proteins and their annotated locations for XP_011510789.1

    Conserved Domains (1) summary
    pfam00003
    Location:1231
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
  5. XM_011512488.2XP_011510790.1  probable G-protein coupled receptor 156 isoform X4

RNA

  1. XR_924107.3 RNA Sequence

Support Center