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Kif11 kinesin family member 11 [ Mus musculus (house mouse) ]

Gene ID: 16551, updated on 9-Aug-2021

Summary

Official Symbol
Kif11provided by MGI
Official Full Name
kinesin family member 11provided by MGI
Primary source
MGI:MGI:1098231
See related
Ensembl:ENSMUSG00000012443
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Kn; Eg5; Kif; Kif8; Kifl1; Knsl1
Expression
Biased expression in CNS E11.5 (RPKM 30.5), liver E14 (RPKM 27.0) and 10 other tissues See more
Orthologs
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Genomic context

See Kif11 in Genome Data Viewer
Location:
19; 19 C2
Exon count:
22
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (37364830..37410311)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (37376382..37421863)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (37450893..37496349)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4931408D14 gene Neighboring gene insulin degrading enzyme Neighboring gene ribosomal protein L10, pseudogene 6 Neighboring gene mortality factor 4 like 1 pseudogene Neighboring gene predicted gene, 46649 Neighboring gene hematopoietically expressed homeobox Neighboring gene RIKEN cDNA 1700122C19 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables plus-end-directed microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in microtubule-based movement IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within mitotic centrosome separation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitotic spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitotic spindle assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of mitotic centrosome separation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within spindle assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spindle organization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in microtubule ISO
Inferred from Sequence Orthology
more info
 
located_in mitotic spindle ISO
Inferred from Sequence Orthology
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
located_in spindle ISO
Inferred from Sequence Orthology
more info
 
is_active_in spindle microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with spindle microtubule ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with spindle pole ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
kinesin-like protein KIF11
Names
kinesin-like 1
kinesin-related motor protein Eg5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010615.2NP_034745.1  kinesin-like protein KIF11

    See identical proteins and their annotated locations for NP_034745.1

    Status: VALIDATED

    Source sequence(s)
    BC060670, BY097786, CJ206639
    Consensus CDS
    CCDS29777.1
    UniProtKB/Swiss-Prot
    Q6P9P6
    Related
    ENSMUSP00000012587.4, ENSMUST00000012587.4
    Conserved Domains (3) summary
    smart00129
    Location:17365
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01364
    Location:15367
    KISc_BimC_Eg5; Kinesin motor domain, BimC/Eg5 spindle pole proteins
    pfam13931
    Location:9151047
    Microtub_bind; Kinesin-associated microtubule-binding

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    37364830..37410311
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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