Format

Send to:

Choose Destination

RBMY1F RNA binding motif protein Y-linked family 1 member F [ Homo sapiens (human) ]

Gene ID: 159163, updated on 5-Jan-2022

Summary

Official Symbol
RBMY1Fprovided by HGNC
Official Full Name
RNA binding motif protein Y-linked family 1 member Fprovided by HGNC
Primary source
HGNC:HGNC:23974
See related
Ensembl:ENSG00000169800
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
YRRM2
Summary
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward testis (RPKM 4.8) See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See RBMY1F in Genome Data Viewer
Location:
Yq11.223
Exon count:
14
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) Y NC_000024.10 (22162885..22183008, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) Y NC_000024.9 (24309032..24329070, complement)

Chromosome Y - NC_000024.10Genomic Context describing neighboring genes Neighboring gene PTPN13 like Y-linked 2 Neighboring gene uncharacterized LOC102725532 Neighboring gene testis-specific transcript, Y-linked 6B Neighboring gene testis specific protein Y-linked 23, pseudogene Neighboring gene RNA binding motif protein Y-linked family 2 member U, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC33094

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA binding NAS
Non-traceable Author Statement
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in spermatogenesis NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
RNA-binding motif protein, Y chromosome, family 1 member F/J
Names
y chromosome RNA recognition motif 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_004755.2 

    Range
    357656..372056 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001303410.2NP_001290339.1  RNA-binding motif protein, Y chromosome, family 1 member F/J isoform 2

    See identical proteins and their annotated locations for NP_001290339.1

    Status: REVIEWED

    Source sequence(s)
    AC023342
    UniProtKB/Swiss-Prot
    Q15415
    Conserved Domains (4) summary
    PHA02896
    Location:247362
    PHA02896; A-type inclusion like protein; Provisional
    COG0724
    Location:1189
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12382
    Location:785
    RRM_RBMX_like; RNA recognition motif in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
    pfam08081
    Location:174218
    RBM1CTR; RBM1CTR (NUC064) family
  2. NM_001382381.1NP_001369310.1  RNA-binding motif protein, Y chromosome, family 1 member F/J isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC023342
    Related
    ENSP00000406005.2, ENST00000454978.2
    Conserved Domains (4) summary
    COG0724
    Location:1189
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    PRK14086
    Location:158316
    dnaA; chromosomal replication initiator protein DnaA
    pfam08081
    Location:174218
    RBM1CTR; RBM1CTR (NUC064) family
    cd12382
    Location:785
    RRM_RBMX_like; RNA recognition motif (RRM) found in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
  3. NM_001382382.1NP_001369311.1  RNA-binding motif protein, Y chromosome, family 1 member F/J isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC023342
    Conserved Domains (4) summary
    COG0724
    Location:1189
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    PRK14086
    Location:158316
    dnaA; chromosomal replication initiator protein DnaA
    pfam08081
    Location:174218
    RBM1CTR; RBM1CTR (NUC064) family
    cd12382
    Location:785
    RRM_RBMX_like; RNA recognition motif (RRM) found in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
  4. NM_001382383.1NP_001369312.1  RNA-binding motif protein, Y chromosome, family 1 member F/J isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC023342
    Conserved Domains (4) summary
    COG0724
    Location:1189
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    PRK14086
    Location:158316
    dnaA; chromosomal replication initiator protein DnaA
    pfam08081
    Location:174218
    RBM1CTR; RBM1CTR (NUC064) family
    cd12382
    Location:785
    RRM_RBMX_like; RNA recognition motif (RRM) found in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
  5. NM_001382384.1NP_001369313.1  RNA-binding motif protein, Y chromosome, family 1 member F/J isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC023342
    Conserved Domains (4) summary
    COG0724
    Location:1189
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    PRK14086
    Location:158316
    dnaA; chromosomal replication initiator protein DnaA
    pfam08081
    Location:174218
    RBM1CTR; RBM1CTR (NUC064) family
    cd12382
    Location:785
    RRM_RBMX_like; RNA recognition motif (RRM) found in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
  6. NM_152585.3NP_689798.1  RNA-binding motif protein, Y chromosome, family 1 member F/J isoform 1

    See identical proteins and their annotated locations for NP_689798.1

    Status: REVIEWED

    Source sequence(s)
    AC023342
    Consensus CDS
    CCDS35483.1
    UniProtKB/Swiss-Prot
    Q15415
    Related
    ENSP00000307155.7, ENST00000303766.12
    Conserved Domains (4) summary
    COG0724
    Location:1189
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12382
    Location:785
    RRM_RBMX_like; RNA recognition motif in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
    pfam08081
    Location:174218
    RBM1CTR; RBM1CTR (NUC064) family
    cl28271
    Location:158316
    dnaA; chromosomal replication initiation protein; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000024.10 Reference GRCh38.p13 Primary Assembly

    Range
    22162885..22183008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017030033.1XP_016885522.1  RNA-binding motif protein, Y chromosome, family 1 member F/J isoform X3

  2. XM_024452489.1XP_024308257.1  RNA-binding motif protein, Y chromosome, family 1 member F/J isoform X1

    Conserved Domains (3) summary
    COG0724
    Location:1189
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12382
    Location:785
    RRM_RBMX_like; RNA recognition motif in heterogeneous nuclear ribonucleoprotein G (hnRNP G), Y chromosome RNA recognition motif 1 (hRBMY), testis-specific heterogeneous nuclear ribonucleoprotein G-T (hnRNP G-T) and similar proteins
    pfam08081
    Location:174218
    RBM1CTR; RBM1CTR (NUC064) family
  3. XM_017030032.2XP_016885521.1  RNA-binding motif protein, Y chromosome, family 1 member F/J isoform X2

Support Center