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Htr4 5 hydroxytryptamine (serotonin) receptor 4 [ Mus musculus (house mouse) ]

Gene ID: 15562, updated on 12-Mar-2017
Official Symbol
Htr4provided by MGI
Official Full Name
5 hydroxytryptamine (serotonin) receptor 4provided by MGI
Primary source
MGI:MGI:109246
See related
Ensembl:ENSMUSG00000026322
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5-HT4; 5HTR4; 5-HT-4; 5-HT<4L>
Orthologs
Location:
18; 18 E1
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (62322158..62498026)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (62483858..62627456)

Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 46634 Neighboring gene predicted gene 9949 Neighboring gene predicted gene, 36124 Neighboring gene predicted gene, 36316 Neighboring gene X-linked lymphocyte-regulated 5C pseudogene Neighboring gene F-box protein 38 Neighboring gene serine peptidase inhibitor, Kazal type 10 Neighboring gene predicted gene, 36368

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
G-protein coupled serotonin receptor activity ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
trace-amine receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
adenylate cyclase-activating G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
gamma-aminobutyric acid signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
gamma-aminobutyric acid signaling pathway ISO
Inferred from Sequence Orthology
more info
 
regulation of appetite IEA
Inferred from Electronic Annotation
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
endosome IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
5-hydroxytryptamine receptor 4
Names
serotonin receptor 4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008313.4NP_032339.2  5-hydroxytryptamine receptor 4

    See identical proteins and their annotated locations for NP_032339.2

    Status: PROVISIONAL

    Source sequence(s)
    AC131714, AC152454
    Consensus CDS
    CCDS29291.1
    UniProtKB/Swiss-Prot
    P97288
    Related
    ENSMUSP00000027560, ENSMUST00000027560
    Conserved Domains (2) summary
    pfam00001
    Location:36312
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam05296
    Location:21329
    TAS2R; Taste receptor protein (TAS2R)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

    Range
    62322158..62498026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006525683.3XP_006525746.1  5-hydroxytryptamine receptor 4 isoform X4

    See identical proteins and their annotated locations for XP_006525746.1

    UniProtKB/Swiss-Prot
    P97288
    Conserved Domains (2) summary
    pfam00001
    Location:36312
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam05296
    Location:21329
    TAS2R; Taste receptor protein (TAS2R)
  2. XM_006525682.3XP_006525745.1  5-hydroxytryptamine receptor 4 isoform X3

    See identical proteins and their annotated locations for XP_006525745.1

    Conserved Domains (2) summary
    pfam00001
    Location:36312
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam05296
    Location:21329
    TAS2R; Taste receptor protein (TAS2R)
  3. XM_006525681.3XP_006525744.1  5-hydroxytryptamine receptor 4 isoform X3

    See identical proteins and their annotated locations for XP_006525744.1

    Conserved Domains (2) summary
    pfam00001
    Location:36312
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam05296
    Location:21329
    TAS2R; Taste receptor protein (TAS2R)
  4. XM_006525680.3XP_006525743.1  5-hydroxytryptamine receptor 4 isoform X2

    See identical proteins and their annotated locations for XP_006525743.1

    UniProtKB/Swiss-Prot
    P97288
    Conserved Domains (2) summary
    pfam00001
    Location:36312
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam05296
    Location:21329
    TAS2R; Taste receptor protein (TAS2R)
  5. XM_011246848.2XP_011245150.1  5-hydroxytryptamine receptor 4 isoform X5

    Conserved Domains (2) summary
    pfam00001
    Location:36312
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam05296
    Location:21329
    TAS2R; Taste receptor protein (TAS2R)
  6. XM_017317839.1XP_017173328.1  5-hydroxytryptamine receptor 4 isoform X1

    UniProtKB/Swiss-Prot
    P97288
    Conserved Domains (2) summary
    pfam00001
    Location:36312
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam05296
    Location:21329
    TAS2R; Taste receptor protein (TAS2R)
  7. XM_006525676.3XP_006525739.1  5-hydroxytryptamine receptor 4 isoform X1

    See identical proteins and their annotated locations for XP_006525739.1

    UniProtKB/Swiss-Prot
    P97288
    Conserved Domains (2) summary
    pfam00001
    Location:36312
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam05296
    Location:21329
    TAS2R; Taste receptor protein (TAS2R)
  8. XM_006525678.3XP_006525741.1  5-hydroxytryptamine receptor 4 isoform X1

    See identical proteins and their annotated locations for XP_006525741.1

    UniProtKB/Swiss-Prot
    P97288
    Conserved Domains (2) summary
    pfam00001
    Location:36312
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam05296
    Location:21329
    TAS2R; Taste receptor protein (TAS2R)
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