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SLC2A7 solute carrier family 2 member 7 [ Homo sapiens (human) ]

Gene ID: 155184, updated on 26-Nov-2021

Summary

Official Symbol
SLC2A7provided by HGNC
Official Full Name
solute carrier family 2 member 7provided by HGNC
Primary source
HGNC:HGNC:13445
See related
Ensembl:ENSG00000197241 MIM:610371
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GLUT7; GLUT-7; hGLUT7
Summary
SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Li et al., 2004). This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See SLC2A7 in Genome Data Viewer
Location:
1p36.23
Exon count:
14
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (8992534..9026423, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (9063032..9086482, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 1652 Neighboring gene carbonic anhydrase 6 Neighboring gene RNA, 7SL, cytoplasmic 451, pseudogene Neighboring gene solute carrier family 2 member 5 Neighboring gene G protein-coupled receptor 157

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
solute carrier family 2, facilitated glucose transporter member 7
Names
glucose transporter type 7
intestinal facilitative glucose transporter 7
solute carrier family 2 (facilitated glucose transporter), member 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207420.3NP_997303.2  solute carrier family 2, facilitated glucose transporter member 7

    See identical proteins and their annotated locations for NP_997303.2

    Status: VALIDATED

    Source sequence(s)
    AL158048
    Consensus CDS
    CCDS98.2
    UniProtKB/Swiss-Prot
    Q6PXP3
    Related
    ENSP00000383698.1, ENST00000400906.2
    Conserved Domains (1) summary
    cd17432
    Location:26477
    MFS_GLUT_Class2; Class 2 Glucose transporters (GLUTs) of the Major Facilitator Superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    8992534..9026423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011540824.2XP_011539126.1  solute carrier family 2, facilitated glucose transporter member 7 isoform X1

    Conserved Domains (2) summary
    cd06174
    Location:100439
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:26441
    Sugar_tr; Sugar (and other) transporter
  2. XM_011540825.2XP_011539127.1  solute carrier family 2, facilitated glucose transporter member 7 isoform X2

    Conserved Domains (1) summary
    cd06174
    Location:100367
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
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