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FAM81B family with sequence similarity 81 member B [ Homo sapiens (human) ]

Gene ID: 153643, updated on 13-May-2022

Summary

Official Symbol
FAM81Bprovided by HGNC
Official Full Name
family with sequence similarity 81 member Bprovided by HGNC
Primary source
HGNC:HGNC:26335
See related
Ensembl:ENSG00000153347 AllianceGenome:HGNC:26335
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 29.2) See more
Orthologs
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Genomic context

See FAM81B in Genome Data Viewer
Location:
5q15
Exon count:
14
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (95391366..95450441)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (95892268..95951364)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (94727070..94786145)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene multiple C2 and transmembrane domain containing 1 Neighboring gene uncharacterized LOC105379085 Neighboring gene uncharacterized LOC105379089 Neighboring gene RTRAF pseudogene 2 Neighboring gene SKI3 subunit of superkiller complex Neighboring gene RNA, U6 small nuclear 308, pseudogene Neighboring gene arylsulfatase family member K

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ25333

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus HDA PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152548.3NP_689761.2  protein FAM81B

    Status: VALIDATED

    Source sequence(s)
    AC090071, AK058062, BC034772, BM560335
    Consensus CDS
    CCDS43341.1
    UniProtKB/Swiss-Prot
    Q96LP2
    Related
    ENSP00000283357.5, ENST00000283357.10
    Conserved Domains (1) summary
    COG1196
    Location:145452
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    95391366..95450441
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011543207.2XP_011541509.1  protein FAM81B isoform X1

  2. XM_047416821.1XP_047272777.1  protein FAM81B isoform X2

  3. XM_047416822.1XP_047272778.1  protein FAM81B isoform X4

  4. XM_011543209.2XP_011541511.1  protein FAM81B isoform X3

    Conserved Domains (1) summary
    COG1196
    Location:64356
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  5. XM_011543210.3XP_011541512.1  protein FAM81B isoform X5

    See identical proteins and their annotated locations for XP_011541512.1

    Conserved Domains (1) summary
    PRK12704
    Location:151258
    PRK12704; phosphodiesterase; Provisional
  6. XM_047416823.1XP_047272779.1  protein FAM81B isoform X6

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    95892268..95951364
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)