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DNAJB7 DnaJ heat shock protein family (Hsp40) member B7 [ Homo sapiens (human) ]

Gene ID: 150353, updated on 13-Mar-2020

Summary

Official Symbol
DNAJB7provided by HGNC
Official Full Name
DnaJ heat shock protein family (Hsp40) member B7provided by HGNC
Primary source
HGNC:HGNC:24986
See related
Ensembl:ENSG00000172404 MIM:611336
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DJ5; HSC3
Summary
The protein encoded by this intronless gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain.[provided by RefSeq, Mar 2011]
Orthologs

Genomic context

See DNAJB7 in Genome Data Viewer
Location:
22q13.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (40859549..40862113, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (41255553..41258130, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 17 Neighboring gene microRNA 4766 Neighboring gene ST13 Hsp70 interacting protein Neighboring gene X-prolyl aminopeptidase 3 Neighboring gene RNA, U6 small nuclear 379, pseudogene Neighboring gene ring-box 1

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC138340

Gene Ontology Provided by GOA

Function Evidence Code Pubs
chaperone binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
dnaJ homolog subfamily B member 7
Names
DnaJ (Hsp40) homolog, subfamily B, member 7
novel DnaJ domain protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145174.2NP_660157.1  dnaJ homolog subfamily B member 7

    See identical proteins and their annotated locations for NP_660157.1

    Status: VALIDATED

    Source sequence(s)
    AF085232
    Consensus CDS
    CCDS14008.1
    UniProtKB/Swiss-Prot
    Q7Z6W7
    Related
    ENSP00000307197.4, ENST00000307221.5
    Conserved Domains (2) summary
    COG0484
    Location:2101
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    pfam00226
    Location:366
    DnaJ; DnaJ domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

    Range
    40859549..40862113 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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