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CNIH3 cornichon family AMPA receptor auxiliary protein 3 [ Homo sapiens (human) ]

Gene ID: 149111, updated on 7-Jun-2020

Summary

Official Symbol
CNIH3provided by HGNC
Official Full Name
cornichon family AMPA receptor auxiliary protein 3provided by HGNC
Primary source
HGNC:HGNC:26802
See related
Ensembl:ENSG00000143786
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CNIH-3
Expression
Biased expression in brain (RPKM 4.8), testis (RPKM 1.6) and 10 other tissues See more
Orthologs

Genomic context

See CNIH3 in Genome Data Viewer
Location:
1q42.12
Exon count:
13
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (224434640..224740554)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (224734563..224928269)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene cornichon family AMPA receptor auxiliary protein 4 Neighboring gene WD repeat domain 26 Neighboring gene microRNA 4742 Neighboring gene aldehyde reductase family 1 member B1 pseudogene 1 Neighboring gene CNIH3 antisense RNA 2 Neighboring gene DNAJB6 pseudogene 6 Neighboring gene CNIH3 antisense RNA 1 Neighboring gene long intergenic non-protein coding RNA 2813 Neighboring gene uncharacterized LOC105373108

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ38993

Gene Ontology Provided by GOA

Function Evidence Code Pubs
channel regulator activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
COPII vesicle coating TAS
Traceable Author Statement
more info
 
ER to Golgi vesicle-mediated transport TAS
Traceable Author Statement
more info
 
regulation of AMPA receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 
synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
AMPA glutamate receptor complex ISS
Inferred from Sequence or Structural Similarity
more info
 
ER to Golgi transport vesicle membrane TAS
Traceable Author Statement
more info
 
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
dendritic shaft ISS
Inferred from Sequence or Structural Similarity
more info
 
endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 
endoplasmic reticulum-Golgi intermediate compartment membrane TAS
Traceable Author Statement
more info
 
postsynaptic membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
protein cornichon homolog 3
Names
cornichon homolog 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001322302.2NP_001309231.1  protein cornichon homolog 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC099790, AL596330
    Conserved Domains (1) summary
    pfam03311
    Location:56179
    Cornichon; Cornichon protein
  2. NM_001322303.2NP_001309232.1  protein cornichon homolog 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC099790, AL596330
    Conserved Domains (1) summary
    pfam03311
    Location:27157
    Cornichon; Cornichon protein
  3. NM_001322304.2NP_001309233.1  protein cornichon homolog 3 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330
    Conserved Domains (1) summary
    pfam03311
    Location:10133
    Cornichon; Cornichon protein
  4. NM_001322305.2NP_001309234.1  protein cornichon homolog 3 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC096537, AL596330
    Conserved Domains (1) summary
    pfam03311
    Location:7135
    Cornichon; Cornichon protein
  5. NM_152495.2NP_689708.1  protein cornichon homolog 3 isoform 1

    See identical proteins and their annotated locations for NP_689708.1

    Status: VALIDATED

    Source sequence(s)
    AC096537, AK096312, AL596330
    Consensus CDS
    CCDS1544.1
    UniProtKB/Swiss-Prot
    Q8TBE1
    Related
    ENSP00000272133.3, ENST00000272133.4
    Conserved Domains (1) summary
    pfam03311
    Location:7151
    Cornichon; Cornichon protein

RNA

  1. NR_136287.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AL596330
  2. NR_136288.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330
  3. NR_136289.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330
  4. NR_136290.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330
  5. NR_136291.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330
  6. NR_136292.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330
  7. NR_136293.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330
  8. NR_136294.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330
  9. NR_136295.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330
  10. NR_136296.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330
  11. NR_136297.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC096537, AC099790, AL596330

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    224434640..224740554
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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