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C1orf74 chromosome 1 open reading frame 74 [ Homo sapiens (human) ]

Gene ID: 148304, updated on 25-Jan-2022

Summary

Official Symbol
C1orf74provided by HGNC
Official Full Name
chromosome 1 open reading frame 74provided by HGNC
Primary source
HGNC:HGNC:26319
See related
Ensembl:ENSG00000162757 AllianceGenome:HGNC:26319
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
URLC4
Expression
Broad expression in lymph node (RPKM 8.4), spleen (RPKM 5.4) and 24 other tissues See more
Orthologs
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Genomic context

See C1orf74 in Genome Data Viewer
Location:
1q32.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (209779208..209784559, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (209952553..209957904, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene HSD11B1 antisense RNA 1 Neighboring gene hydroxysteroid 11-beta dehydrogenase 1 Neighboring gene adenosine A2b receptor pseudogene 1 Neighboring gene TRAF3 interacting protein 3 Neighboring gene interferon regulatory factor 6 Neighboring gene VISTA enhancer hs932

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: IRF6

Homology

Clone Names

  • FLJ12736, FLJ25078

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
UPF0739 protein C1orf74
Names
up-regulated in lung cancer 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152485.4NP_689698.1  UPF0739 protein C1orf74

    See identical proteins and their annotated locations for NP_689698.1

    Status: VALIDATED

    Source sequence(s)
    AB101206, AI922337, AK022798, AL022398
    Consensus CDS
    CCDS1491.1
    UniProtKB/Swiss-Prot
    Q96LT6
    UniProtKB/TrEMBL
    A0A0A8K8E6
    Related
    ENSP00000294811.1, ENST00000294811.2
    Conserved Domains (1) summary
    pfam14953
    Location:21268
    DUF4504; Domain of unknown function (DUF4504)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    209779208..209784559 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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