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Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial [ Mus musculus (house mouse) ]

Gene ID: 14719, updated on 23-May-2018

Summary

Official Symbol
Got2provided by MGI
Official Full Name
glutamatic-oxaloacetic transaminase 2, mitochondrialprovided by MGI
Primary source
MGI:MGI:95792
See related
Ensembl:ENSMUSG00000031672 Vega:OTTMUSG00000016488
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Got-2; Kyat4; mAspAT; FABP-pm; AL022787
Expression
Ubiquitous expression in heart adult (RPKM 277.4), liver adult (RPKM 151.9) and 26 other tissues See more
Orthologs

Genomic context

See Got2 in Genome Data Viewer
Location:
8 D1; 8 47.79 cM
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (95864137..95888365, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (98388037..98412265, complement)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31805 Neighboring gene solute carrier family 38, member 7 Neighboring gene predicted gene 8637 Neighboring gene predicted gene, 31892

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

Clone Names

  • MGC102129, MGC115763

Gene Ontology Provided by MGI

Function Evidence Code Pubs
L-aspartate:2-oxoglutarate aminotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
L-aspartate:2-oxoglutarate aminotransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
L-aspartate:2-oxoglutarate aminotransferase activity ISO
Inferred from Sequence Orthology
more info
 
L-phenylalanine:2-oxoglutarate aminotransferase activity IEA
Inferred from Electronic Annotation
more info
 
amino acid binding ISO
Inferred from Sequence Orthology
more info
 
carboxylic acid binding ISO
Inferred from Sequence Orthology
more info
 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
kynurenine-oxoglutarate transaminase activity IEA
Inferred from Electronic Annotation
more info
 
phospholipid binding ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
pyridoxal phosphate binding ISO
Inferred from Sequence Orthology
more info
 
transaminase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
aspartate biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
aspartate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
aspartate catabolic process ISO
Inferred from Sequence Orthology
more info
 
aspartate metabolic process ISO
Inferred from Sequence Orthology
more info
 
biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
cellular amino acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
dicarboxylic acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
glutamate catabolic process to 2-oxoglutarate IDA
Inferred from Direct Assay
more info
PubMed 
glutamate catabolic process to 2-oxoglutarate ISO
Inferred from Sequence Orthology
more info
 
glutamate catabolic process to aspartate IDA
Inferred from Direct Assay
more info
PubMed 
lipid transport IEA
Inferred from Electronic Annotation
more info
 
oxaloacetate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
oxaloacetate metabolic process ISO
Inferred from Sequence Orthology
more info
 
response to ethanol ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
T-tubule ISO
Inferred from Sequence Orthology
more info
 
cell surface ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane HDA PubMed 
mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrion HDA PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
myelin sheath IDA
Inferred from Direct Assay
more info
PubMed 
perikaryon ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
sarcolemma ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
aspartate aminotransferase, mitochondrial
Names
FABP-1
FABPpm
fatty acid-binding protein
glutamate oxaloacetate transaminase 2, mitochondrial
kynurenine aminotransferase 4
kynurenine aminotransferase IV
kynurenine--oxoglutarate transaminase 4
kynurenine--oxoglutarate transaminase IV
mitochondrial aspartate aminotransferase
plasma membrane fatty acid binding protein
plasma membrane-associated fatty acid-binding protein
transaminase A
NP_034455.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010325.2NP_034455.1  aspartate aminotransferase, mitochondrial

    See identical proteins and their annotated locations for NP_034455.1

    Status: PROVISIONAL

    Source sequence(s)
    AC127300
    Consensus CDS
    CCDS22568.1
    UniProtKB/Swiss-Prot
    P05202
    Related
    ENSMUSP00000034097.7, OTTMUSP00000017748, ENSMUST00000034097.7, OTTMUST00000039785
    Conserved Domains (2) summary
    PLN02397
    Location:32430
    PLN02397; aspartate transaminase
    pfam00155
    Location:57425
    Aminotran_1_2; Aminotransferase class I and II

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

    Range
    95864137..95888365 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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