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TMCO5A transmembrane and coiled-coil domains 5A [ Homo sapiens (human) ]

Gene ID: 145942, updated on 21-Dec-2019

Summary

Official Symbol
TMCO5Aprovided by HGNC
Official Full Name
transmembrane and coiled-coil domains 5Aprovided by HGNC
Primary source
HGNC:HGNC:28558
See related
Ensembl:ENSG00000166069
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TMCO5
Expression
Restricted expression toward testis (RPKM 13.4) See more
Orthologs

Genomic context

See TMCO5A in Genome Data Viewer
Location:
15q14
Exon count:
16
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (37934607..37997541)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (38226801..38243623)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370773 Neighboring gene VISTA enhancer hs830 Neighboring gene uncharacterized LOC107984774 Neighboring gene long intergenic non-protein coding RNA 2345 Neighboring gene long intergenic non-protein coding RNA 1852

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ35807, MGC35118

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane and coiled-coil domain-containing protein 5A
Names
testicular tissue protein Li 205
transmembrane and coiled-coil domains 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_052635.1 RefSeqGene

    Range
    5001..38118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001330255.1NP_001317184.1  transmembrane and coiled-coil domain-containing protein 5A isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate 3' terminal exon, resulting in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC091005, AK093126, BI561792
    Consensus CDS
    CCDS81862.1
    UniProtKB/Swiss-Prot
    Q8N6Q1
    Related
    ENSP00000454112.1, ENST00000559502.5
    Conserved Domains (1) summary
    pfam14992
    Location:15223
    TMCO5; TMCO5 family
  2. NM_001370735.1NP_001357664.1  transmembrane and coiled-coil domain-containing protein 5A isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC091005
    Related
    ENSP00000327234.4, ENST00000319669.4
    Conserved Domains (1) summary
    pfam14992
    Location:15287
    TMCO5; TMCO5 family
  3. NM_001370736.1NP_001357665.1  transmembrane and coiled-coil domain-containing protein 5A isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC091005
    Conserved Domains (1) summary
    pfam14992
    Location:29301
    TMCO5; TMCO5 family
  4. NM_001370737.1NP_001357666.1  transmembrane and coiled-coil domain-containing protein 5A isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC091005
    Conserved Domains (1) summary
    pfam14992
    Location:15223
    TMCO5; TMCO5 family
  5. NM_152453.3NP_689666.2  transmembrane and coiled-coil domain-containing protein 5A isoform 1

    See identical proteins and their annotated locations for NP_689666.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    BC029221, BI561792, BI826726
    Consensus CDS
    CCDS10046.1
    UniProtKB/Swiss-Prot
    Q8N6Q1
    UniProtKB/TrEMBL
    A0A024R9I9
    Conserved Domains (1) summary
    pfam14992
    Location:15287
    TMCO5; TMCO5 family

RNA

  1. NR_163584.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC091005
  2. NR_163585.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC091005

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    37934607..37997541
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011521262.2XP_011519564.1  transmembrane and coiled-coil domain-containing protein 5A isoform X2

    Conserved Domains (1) summary
    pfam14992
    Location:15223
    TMCO5; TMCO5 family
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