Format

Send to:

Choose Destination

HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 [ Homo sapiens (human) ]

Gene ID: 144983, updated on 12-Aug-2018

Summary

Official Symbol
HNRNPA1L2provided by HGNC
Official Full Name
heterogeneous nuclear ribonucleoprotein A1-like 2provided by HGNC
Primary source
HGNC:HGNC:27067
See related
Ensembl:ENSG00000139675 Vega:OTTHUMG00000016972
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in ovary (RPKM 119.2), bone marrow (RPKM 68.3) and 25 other tissues See more
Orthologs

Genomic context

See HNRNPA1L2 in Genome Data Viewer
Location:
13q14.3
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 13 NC_000013.11 (52617470..52643784)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (53173750..53217931)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene cytoskeleton associated protein 2 Neighboring gene long intergenic non-protein coding RNA 345 Neighboring gene transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 3 Neighboring gene mitochondrial ribosomal protein S31 pseudogene 4 Neighboring gene SGT1 homolog, MIS12 kinetochore complex assembly cochaperone Neighboring gene chondromodulin

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Pathways from BioSystems

  • Spliceosome, organism-specific biosystem (from KEGG)
    Spliceosome, organism-specific biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
  • Spliceosome, conserved biosystem (from KEGG)
    Spliceosome, conserved biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC102957

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA binding IEA
Inferred from Electronic Annotation
more info
 
mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
mRNA transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
heterogeneous nuclear ribonucleoprotein A1-like 2
Names
hnRNP A1-like 2
hnRNP core protein A1-like 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011724.1NP_001011724.1  heterogeneous nuclear ribonucleoprotein A1-like 2

    See identical proteins and their annotated locations for NP_001011724.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK094423, AL137058, BX477483, CD523364
    Consensus CDS
    CCDS31980.1
    UniProtKB/Swiss-Prot
    Q32P51
    UniProtKB/TrEMBL
    A0A024QZ98
    Conserved Domains (3) summary
    cd12580
    Location:105181
    RRM2_hnRNPA1; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and similar proteins
    pfam11627
    Location:257292
    HnRNPA1; Nuclear factor hnRNPA1
    cl17169
    Location:1292
    RRM_SF; RNA recognition motif (RRM) superfamily
  2. NM_001011725.1NP_001011725.1  heterogeneous nuclear ribonucleoprotein A1-like 2

    See identical proteins and their annotated locations for NP_001011725.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL137058, BQ425201, BX477483
    Consensus CDS
    CCDS31980.1
    UniProtKB/Swiss-Prot
    Q32P51
    UniProtKB/TrEMBL
    A0A024QZ98
    Related
    ENSP00000350090.2, OTTHUMP00000018460, ENST00000357495.3, OTTHUMT00000045098
    Conserved Domains (3) summary
    cd12580
    Location:105181
    RRM2_hnRNPA1; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and similar proteins
    pfam11627
    Location:257292
    HnRNPA1; Nuclear factor hnRNPA1
    cl17169
    Location:1292
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p12 Primary Assembly

    Range
    52617470..52643784
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center