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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001312900.1 → NP_001299829.1 glutamate decarboxylase 1 isoform GAD25
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) contains an alternate terminal exon in place of the last eleven exons compared to variant 1. The resulting isoform (GAD25) has a shorter and distinct C-terminus compared to isoform GAD67.
- Source sequence(s)
-
BY265972, KM102984
- Consensus CDS
-
CCDS84535.1
- UniProtKB/TrEMBL
- A0A6P5R201, A0A8C6GIQ3, D3Z1L8
- Related
- ENSMUSP00000119733.2, ENSMUST00000148210.8
- Conserved Domains (1) summary
-
- cl18945
Location:143 → 212
- AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
-
NM_008077.5 → NP_032103.2 glutamate decarboxylase 1 isoform GAD67
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (GAD67).
- Source sequence(s)
-
AI845043, AK148497, BY265972
- Consensus CDS
-
CCDS16108.1
- UniProtKB/Swiss-Prot
- O08685, P48318
- UniProtKB/TrEMBL
- A0A6P5QUQ4, A0A8C6GJJ2, Q548L6
- Related
- ENSMUSP00000092539.5, ENSMUST00000094934.11
- Conserved Domains (1) summary
-
- pfam00282
Location:143 → 517
- Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain