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OR2AG1 olfactory receptor family 2 subfamily AG member 1 [ Homo sapiens (human) ]

Gene ID: 144125, updated on 11-Jun-2021

Summary

Official Symbol
OR2AG1provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily AG member 1provided by HGNC
Primary source
HGNC:HGNC:15142
See related
Ensembl:ENSG00000279486
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR2AG3; OR11-79
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015]
Orthologs
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Genomic context

See OR2AG1 in Genome Data Viewer
Location:
11p15.4
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (6783020..6791558)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (6804251..6812789)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene GTPase, very large interferon inducible pseudogene 2 Neighboring gene olfactory receptor family 2 subfamily AG member 2 Neighboring gene olfactory receptor family 6 subfamily A member 2 Neighboring gene phosphorylated adaptor for RNA export pseudogene

Genomic regions, transcripts, and products

Bibliography

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 2AG1
Names
hT3 olfactory receptor
olfactory receptor 2AG3
olfactory receptor OR11-79
olfactory receptor, family 2, subfamily AG, member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004489.3NP_001004489.1  olfactory receptor 2AG1

    See identical proteins and their annotated locations for NP_001004489.1

    Status: VALIDATED

    Source sequence(s)
    AC087280
    Consensus CDS
    CCDS31414.1
    UniProtKB/Swiss-Prot
    Q9H205
    UniProtKB/TrEMBL
    A0A126GVD0
    Related
    ENSP00000493074.1, ENST00000641258.1
    Conserved Domains (2) summary
    pfam00001
    Location:42290
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:34305
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    6783020..6791558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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