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CWF19L2 CWF19 like cell cycle control factor 2 [ Homo sapiens (human) ]

Gene ID: 143884, updated on 23-Nov-2021

Summary

Official Symbol
CWF19L2provided by HGNC
Official Full Name
CWF19 like cell cycle control factor 2provided by HGNC
Primary source
HGNC:HGNC:26508
See related
Ensembl:ENSG00000152404
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in ovary (RPKM 6.7), endometrium (RPKM 5.9) and 25 other tissues See more
Orthologs
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Genomic context

See CWF19L2 in Genome Data Viewer
Location:
11q22.3
Exon count:
20
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (107326356..107457839, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (107197071..107328572, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene argininosuccinate synthetase 1 pseudogene 13 Neighboring gene uncharacterized LOC105369477 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 pseudogene 1 Neighboring gene alkB homolog 8, tRNA methyltransferase Neighboring gene SUCLG2 pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32343

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of post-mRNA release spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
CWF19-like protein 2
Names
CWF19 like 2, cell cycle control

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152434.3NP_689647.2  CWF19-like protein 2

    See identical proteins and their annotated locations for NP_689647.2

    Status: VALIDATED

    Source sequence(s)
    AK126881, BX648704
    Consensus CDS
    CCDS8336.2
    UniProtKB/Swiss-Prot
    Q2TBE0
    Related
    ENSP00000282251.5, ENST00000282251.9
    Conserved Domains (2) summary
    pfam04676
    Location:795889
    CwfJ_C_2; Protein similar to CwfJ C-terminus 2
    cl00228
    Location:662786
    HIT_like; HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    107326356..107457839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017017239.2XP_016872728.1  CWF19-like protein 2 isoform X2

    Conserved Domains (2) summary
    pfam04676
    Location:319413
    CwfJ_C_2; Protein similar to CwfJ C-terminus 2
    cl00228
    Location:186310
    HIT_like; HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis ...
  2. XM_011542620.3XP_011540922.1  CWF19-like protein 2 isoform X1

RNA

  1. XR_947795.2 RNA Sequence

    Related
    ENST00000431778.5
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