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Fv1 Friend virus susceptibility 1 [ Mus musculus (house mouse) ]

Gene ID: 14349, updated on 12-Mar-2024


Official Symbol
Fv1provided by MGI
Official Full Name
Friend virus susceptibility 1provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000070583 AllianceGenome:MGI:95595
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rv1; Fv-1; Fv1d; Rv-1
Acts upstream of or within response to virus. Located in Golgi apparatus. Is expressed in several structures, including endocrine gland; ganglia; nasal cavity epithelium; submandibular gland primordium; and thymus primordium. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

4 E1; 4 78.56 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (147953436..147954815)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (147868979..147870358)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S19, pseudogene 3 Neighboring gene zinc finger protein 933 Neighboring gene STARR-positive B cell enhancer ABC_E4726 Neighboring gene STARR-positive B cell enhancer ABC_E181 Neighboring gene migration and invasion inhibitory protein Neighboring gene mitofusin 2 Neighboring gene STARR-positive B cell enhancer ABC_E9625 Neighboring gene procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

Genomic regions, transcripts, and products


GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within defense response to virus IEA
Inferred from Electronic Annotation
more info
involved_in response to virus IBA
Inferred from Biological aspect of Ancestor
more info
acts_upstream_of_or_within response to virus IDA
Inferred from Direct Assay
more info
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info

General protein information

Preferred Names
Friend virus susceptibility protein 1
Fv1 gammaretrovirus restriction factor
Fv1 restriction factor
Rauscher leukemia virus susceptibility 1
retrovirus restriction protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010244.3NP_034374.2  Friend virus susceptibility protein 1

    See identical proteins and their annotated locations for NP_034374.2

    Status: VALIDATED

    Source sequence(s)
    Consensus CDS
    P70213, P70214
    X2FIS1, X2FP38
    ENSMUSP00000092054.2, ENSMUST00000094481.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000070.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)