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ITLN2 intelectin 2 [ Homo sapiens (human) ]

Gene ID: 142683, updated on 11-Jun-2021

Summary

Official Symbol
ITLN2provided by HGNC
Official Full Name
intelectin 2provided by HGNC
Primary source
HGNC:HGNC:20599
See related
Ensembl:ENSG00000158764 MIM:609874
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HL2; HL-2
Expression
Biased expression in small intestine (RPKM 141.3), duodenum (RPKM 79.7) and 1 other tissue See more
Orthologs
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Genomic context

See ITLN2 in Genome Data Viewer
Location:
1q23.3
Exon count:
10
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (160945020..160957378, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (160914815..160924599, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene intelectin 1 Neighboring gene spermine synthase pseudogene Neighboring gene uncharacterized LOC101928372 Neighboring gene F11 receptor Neighboring gene thiosulfate sulfurtransferase like domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oligosaccharide binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
intelectin-2
Names
endothelial lectin HL-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080878.3NP_543154.1  intelectin-2 precursor

    See identical proteins and their annotated locations for NP_543154.1

    Status: VALIDATED

    Source sequence(s)
    AL354714, AL591806, AY358905
    Consensus CDS
    CCDS1212.1
    UniProtKB/Swiss-Prot
    Q8WWU7
    Related
    ENSP00000357008.3, ENST00000368029.4
    Conserved Domains (1) summary
    cl00085
    Location:4994
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    160945020..160957378 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011509210.1XP_011507512.1  intelectin-2 isoform X1

    See identical proteins and their annotated locations for XP_011507512.1

    UniProtKB/Swiss-Prot
    Q8WWU7
    Conserved Domains (1) summary
    cl00085
    Location:4994
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
  2. XM_024453321.1XP_024309089.1  intelectin-2 isoform X2

    Conserved Domains (1) summary
    cl00085
    Location:4893
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
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