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TCEAL2 transcription elongation factor A like 2 [ Homo sapiens (human) ]

Gene ID: 140597, updated on 11-Jun-2021

Summary

Official Symbol
TCEAL2provided by HGNC
Official Full Name
transcription elongation factor A like 2provided by HGNC
Primary source
HGNC:HGNC:29818
See related
Ensembl:ENSG00000184905
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
WEX1; my048; MY0876G05
Summary
This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. Multiple family members are located on the X chromosome. [provided by RefSeq, Jul 2008]
Expression
Biased expression in brain (RPKM 71.1), ovary (RPKM 27.9) and 8 other tissues See more
Orthologs
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Genomic context

See TCEAL2 in Genome Data Viewer
Location:
Xq22.1
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (102125679..102127712)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (101380651..101382684)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene C3orf49 pseudogene 1 Neighboring gene MT-ND6 pseudogene 13 Neighboring gene uncharacterized LOC105373299 Neighboring gene transcription elongation factor A like 6 Neighboring gene brain expressed X-linked 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables WW domain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transcription elongation factor A protein-like 2
Names
TCEA-like protein 2
transcription elongation factor A (SII)-like 2
transcription elongation factor S-II protein-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012818.1 RefSeqGene

    Range
    4992..7025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080390.4NP_525129.1  transcription elongation factor A protein-like 2

    See identical proteins and their annotated locations for NP_525129.1

    Status: REVIEWED

    Source sequence(s)
    AF325115, AL035214, BM699243, CD580311
    Consensus CDS
    CCDS14496.1
    UniProtKB/Swiss-Prot
    Q9H3H9
    Related
    ENSP00000361866.1, ENST00000372780.6
    Conserved Domains (1) summary
    pfam04538
    Location:123202
    BEX; Brain expressed X-linked like family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    102125679..102127712
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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