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S100A16 S100 calcium binding protein A16 [ Homo sapiens (human) ]

Gene ID: 140576, updated on 13-Mar-2020

Summary

Official Symbol
S100A16provided by HGNC
Official Full Name
S100 calcium binding protein A16provided by HGNC
Primary source
HGNC:HGNC:20441
See related
Ensembl:ENSG00000188643 MIM:617437
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AAG13; S100F; DT1P1A7
Expression
Biased expression in esophagus (RPKM 418.9), skin (RPKM 89.4) and 13 other tissues See more
Orthologs

Genomic context

See S100A16 in Genome Data Viewer
Location:
1q21.3
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (153606883..153613137, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (153579362..153585514, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928034 Neighboring gene S100 calcium binding protein A3 Neighboring gene S100 calcium binding protein A2 Neighboring gene S100 calcium binding protein A14 Neighboring gene S100 calcium binding protein A13 Neighboring gene S100 calcium binding protein A1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC17528

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
response to calcium ion IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome HDA PubMed 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
protein S100-A16
Names
aging-associated gene 13 protein
aging-associated protein 13
protein S100-F

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001317007.1NP_001303936.1  protein S100-A16

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 all encode the same protein.
    Source sequence(s)
    AI673616, BC010541, BQ439720, HY178745
    Consensus CDS
    CCDS1045.1
    UniProtKB/Swiss-Prot
    Q96FQ6
    Related
    ENSP00000357694.1, ENST00000368705.2
    Conserved Domains (1) summary
    cd05022
    Location:699
    S-100A13; S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, ...
  2. NM_001317008.1NP_001303937.1  protein S100-A16

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
    Source sequence(s)
    AI673616, BC010541, HY178745
    Consensus CDS
    CCDS1045.1
    UniProtKB/Swiss-Prot
    Q96FQ6
    Related
    ENSP00000357693.1, ENST00000368704.5
    Conserved Domains (1) summary
    cd05022
    Location:699
    S-100A13; S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, ...
  3. NM_080388.3NP_525127.1  protein S100-A16

    See identical proteins and their annotated locations for NP_525127.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
    Source sequence(s)
    AI673616, BC010541, BM739127
    Consensus CDS
    CCDS1045.1
    UniProtKB/Swiss-Prot
    Q96FQ6
    Related
    ENSP00000357695.3, ENST00000368706.9
    Conserved Domains (1) summary
    cd05022
    Location:699
    S-100A13; S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, ...

RNA

  1. NR_133645.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate first exon and an alternate splice junction compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AI673616, AW954845, BC010541

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    153606883..153613137 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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