Format

Send to:

Choose Destination

Elf1 E74-like factor 1 [ Mus musculus (house mouse) ]

Gene ID: 13709, updated on 31-Jan-2019

Summary

Official Symbol
Elf1provided by MGI
Official Full Name
E74-like factor 1provided by MGI
Primary source
MGI:MGI:107180
See related
Ensembl:ENSMUSG00000036461
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
p70; Sts1; Elf-1; mElf-1
Expression
Ubiquitous expression in thymus adult (RPKM 22.3), bladder adult (RPKM 13.4) and 26 other tissues See more
Orthologs

Genomic context

See Elf1 in Genome Data Viewer
Location:
14; 14 D3
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (79481194..79582491)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (79881001..79982283)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene kelch repeat and BTB (POZ) domain containing 7 Neighboring gene kelch repeat and BTB (POZ) domain containing 6 Neighboring gene WW domain binding protein 4 Neighboring gene nuclear encoded tRNA glutamic acid 4 (anticodon TTC) Neighboring gene claspin homolog pseudogene Neighboring gene SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) Neighboring gene chondromodulin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of T cell receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of cytokine production IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ETS-related transcription factor Elf-1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286411.1NP_001273340.1  ETS-related transcription factor Elf-1 isoform 1

    See identical proteins and their annotated locations for NP_001273340.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein (isoform 1).
    Source sequence(s)
    AK132456, AK142807
    Consensus CDS
    CCDS27301.1
    UniProtKB/Swiss-Prot
    Q60775
    UniProtKB/TrEMBL
    Q3UQ47, Q3V1H4
    Related
    ENSMUSP00000106459.1, ENSMUST00000110835.2
    Conserved Domains (2) summary
    pfam00178
    Location:210289
    Ets; Ets-domain
    pfam12310
    Location:2111
    Elf-1_N; Transcription factor protein N terminal
  2. NM_001286412.1NP_001273341.1  ETS-related transcription factor Elf-1 isoform 2

    See identical proteins and their annotated locations for NP_001273341.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate, in-frame exon in the coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
    Source sequence(s)
    AK132456, AK142807
    UniProtKB/TrEMBL
    Q3UQ47, Q3V1H4
    Related
    ENSMUSP00000153956.1, ENSMUST00000227192.1
    Conserved Domains (2) summary
    pfam00178
    Location:173252
    Ets; Ets-domain
    pfam12310
    Location:284
    Elf-1_N; Transcription factor protein N terminal
  3. NM_007920.4NP_031946.1  ETS-related transcription factor Elf-1 isoform 1

    See identical proteins and their annotated locations for NP_031946.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer protein (isoform 1). Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK132456, AK142807, BC057134
    Consensus CDS
    CCDS27301.1
    UniProtKB/Swiss-Prot
    Q60775
    UniProtKB/TrEMBL
    Q3UQ47, Q3V1H4
    Related
    ENSMUSP00000046515.5, ENSMUST00000040131.12
    Conserved Domains (2) summary
    pfam00178
    Location:210289
    Ets; Ets-domain
    pfam12310
    Location:2111
    Elf-1_N; Transcription factor protein N terminal

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    79481194..79582491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244948.2XP_011243250.1  ETS-related transcription factor Elf-1 isoform X2

    See identical proteins and their annotated locations for XP_011243250.1

    Conserved Domains (2) summary
    pfam00178
    Location:173252
    Ets; Ets-domain
    pfam12310
    Location:284
    Elf-1_N; Transcription factor protein N terminal
  2. XM_011244946.2XP_011243248.1  ETS-related transcription factor Elf-1 isoform X1

    See identical proteins and their annotated locations for XP_011243248.1

    UniProtKB/Swiss-Prot
    Q60775
    UniProtKB/TrEMBL
    Q3V1H4
    Conserved Domains (2) summary
    pfam00178
    Location:210289
    Ets; Ets-domain
    pfam12310
    Location:2111
    Elf-1_N; Transcription factor protein N terminal
  3. XM_011244947.1XP_011243249.1  ETS-related transcription factor Elf-1 isoform X1

    See identical proteins and their annotated locations for XP_011243249.1

    UniProtKB/Swiss-Prot
    Q60775
    UniProtKB/TrEMBL
    Q3V1H4
    Conserved Domains (2) summary
    pfam00178
    Location:210289
    Ets; Ets-domain
    pfam12310
    Location:2111
    Elf-1_N; Transcription factor protein N terminal
Support Center