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OR6B1 olfactory receptor family 6 subfamily B member 1 [ Homo sapiens (human) ]

Gene ID: 135946, updated on 5-Jan-2022

Summary

Official Symbol
OR6B1provided by HGNC
Official Full Name
olfactory receptor family 6 subfamily B member 1provided by HGNC
Primary source
HGNC:HGNC:8354
See related
Ensembl:ENSG00000221813
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR7-3; OR7-9
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR6B1 in Genome Data Viewer
Location:
7q35
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (144000320..144008793)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (143697413..143705886)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily Q member 1 pseudogene Neighboring gene SLC16A1 pseudogene 1 Neighboring gene uncharacterized LOC105375548 Neighboring gene olfactory receptor family 2 subfamily A member 5 Neighboring gene olfactory receptor family 2 subfamily A member 25

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 6B1
Names
olfactory receptor 7-3
olfactory receptor OR7-9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005281.3NP_001005281.1  olfactory receptor 6B1

    See identical proteins and their annotated locations for NP_001005281.1

    Status: VALIDATED

    Source sequence(s)
    AC004853
    Consensus CDS
    CCDS43667.1
    UniProtKB/Swiss-Prot
    O95007
    Related
    ENSP00000492907.1, ENST00000641698.1
    Conserved Domains (1) summary
    cd15224
    Location:26292
    7tmA_OR6B-like; olfactory receptor subfamily 6B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    144000320..144008793
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_018654714.1 Reference GRCh38.p13 PATCHES

    Range
    544550..553023
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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