Dnm1 dynamin 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Dnm1provided by MGI
Official Full Name: dynamin 1provided by MGI
Primary source: MGI:MGI:107384
See related: Ensembl:ENSMUSG00000026825 AllianceGenome:MGI:107384
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Dnm; Ftfl; mKIAA4093
Summary: This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein is a GTPase which is required for membrane recycling, including vesicle endocytosis in neurons. It may also be involved in cellular fission via association with microtubules and actin filaments. Mutations in this gene have been shown to cause seizures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Expression: Biased expression in cerebellum adult (RPKM 188.3), cortex adult (RPKM 160.9) and 14 other tissues See more
Orthologs: human all
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Genomic context

Location:: 2 B; 2 22.09 cM

Exon count:: 27

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (32198483..32243361, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (32308471..32353349, complement)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Dynamin1 long- and short-tail isoforms exploit distinct recruitment and spatial patterns to form endocytic nanoclusters.
Title: Dynamin1 long- and short-tail isoforms exploit distinct recruitment and spatial patterns to form endocytic nanoclusters.
The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3.
Title: The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3.
Sarcolemma wounding activates dynamin-dependent endocytosis in striated muscle.
Title: Sarcolemma wounding activates dynamin-dependent endocytosis in striated muscle.
Tau overexpression impairs neuronal endocytosis by decreasing the GTPase dynamin 1 through the miR-132/MeCP2 pathway.
Title: Tau overexpression impairs neuronal endocytosis by decreasing the GTPase dynamin 1 through the miR-132/MeCP2 pathway.
The present work with dyn1-KO mice further confirms that Ca(2+)-dependent transmitter release is mainly via subquantal mode, suggesting that subquantal release could be also important in other types of cells
Title: Dynamin 1 Restrains Vesicular Release to a Subquantal Mode In Mammalian Adrenal Chromaffin Cells.
Cellular fluorescein hyperfluorescence is dynamin-dependent.
Title: Cellular fluorescein hyperfluorescence is dynamin-dependent and increased by Tetronic 1107 treatment.
dynamin is a molecular motor which would be involved in GLUT4 translocation by facilitating exocytosis
Title: A multiscale study of the role of dynamin in the regulation of glucose uptake.
reveal functional differences between Dnm1a and Dnm1b isoforms in the presence of a challenge, i.e. toxic Dnm1(Ftfl), while reinforcing its effect explicitly in this model of severe pediatric epilepsy
Title: Dynamin 1 isoform roles in a mouse model of severe childhood epileptic encephalopathy.
in the mature epididymis, predominantly localized in clear cells of the distal segments
Title: Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis.
Dynamin may facilitate Fas-mediated apoptotic death in the brain, and Hsp70 may protect by preventing this trafficking.
Title: 70-kDa Heat Shock Protein Downregulates Dynamin in Experimental Stroke: A New Therapeutic Target?

Submit: New GeneRIF Correction See all GeneRIFs (46)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3) 1 citation
Gene trapped (1)
Spontaneous (1) 1 citation
Targeted (8) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI838169 (e-PCR)
- UniSTS:165161

Dnm1 (e-PCR), detects polymorphism
- UniSTS:531529

NoName (e-PCR)
- UniSTS:234370

D2Mit84 (e-PCR), detects polymorphism
- UniSTS:129479

L31397 (e-PCR)
- UniSTS:124895

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables D2 dopamine receptor binding	ISO Inferred from Sequence Orthology more info
enables GDP binding	IDA Inferred from Direct Assay more info	PubMed
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IDA Inferred from Direct Assay more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables GTPase activity	ISO Inferred from Sequence Orthology more info
enables GTPase activity	ISS Inferred from Sequence or Structural Similarity more info
enables SH3 domain binding	ISO Inferred from Sequence Orthology more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables nitric-oxide synthase binding	ISO Inferred from Sequence Orthology more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol-3,4,5-trisphosphate binding	ISO Inferred from Sequence Orthology more info
enables phosphatidylinositol-4,5-bisphosphate binding	ISO Inferred from Sequence Orthology more info
enables phosphatidylinositol-4,5-bisphosphate binding	ISS Inferred from Sequence or Structural Similarity more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info
enables protein homodimerization activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein kinase binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein serine/threonine kinase binding	ISO Inferred from Sequence Orthology more info
enables protein-containing complex binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor internalization	ISO Inferred from Sequence Orthology more info
involved_in clathrin coat assembly involved in endocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in endocytosis	IEA Inferred from Electronic Annotation more info
involved_in endocytosis	ISO Inferred from Sequence Orthology more info
involved_in endosome organization	ISO Inferred from Sequence Orthology more info
involved_in modulation of chemical synaptic transmission	IDA Inferred from Direct Assay more info	PubMed
involved_in modulation of chemical synaptic transmission	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of synaptic vesicle endocytosis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of synaptic vesicle recycling	ISO Inferred from Sequence Orthology more info
involved_in protein homooligomerization	ISO Inferred from Sequence Orthology more info
involved_in protein homotetramerization	ISO Inferred from Sequence Orthology more info
involved_in protein homotetramerization	ISS Inferred from Sequence or Structural Similarity more info
involved_in receptor internalization	ISO Inferred from Sequence Orthology more info
involved_in receptor-mediated endocytosis	IEA Inferred from Electronic Annotation more info
involved_in receptor-mediated endocytosis	ISO Inferred from Sequence Orthology more info
involved_in receptor-mediated endocytosis	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of synaptic vesicle endocytosis	ISO Inferred from Sequence Orthology more info
involved_in regulation of vesicle size	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in synaptic vesicle budding from presynaptic endocytic zone membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in synaptic vesicle endocytosis	IDA Inferred from Direct Assay more info	PubMed
involved_in synaptic vesicle endocytosis	IEA Inferred from Electronic Annotation more info
involved_in synaptic vesicle endocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vesicle scission	ISO Inferred from Sequence Orthology more info
involved_in vesicle scission	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in chromaffin granule	IEA Inferred from Electronic Annotation more info
located_in clathrin-coated pit	IEA Inferred from Electronic Annotation more info
located_in clathrin-coated pit	ISO Inferred from Sequence Orthology more info
located_in clathrin-coated pit	ISS Inferred from Sequence or Structural Similarity more info
located_in clathrin-coated vesicle	ISO Inferred from Sequence Orthology more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in endocytic vesicle	ISO Inferred from Sequence Orthology more info
located_in endocytic vesicle	ISS Inferred from Sequence or Structural Similarity more info
is_active_in glutamatergic synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in glutamatergic synapse	IMP Inferred from Mutant Phenotype more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of membrane coat	IDA Inferred from Direct Assay more info	PubMed
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in myelin sheath	HDA more info	PubMed
located_in photoreceptor inner segment	IDA Inferred from Direct Assay more info	PubMed
located_in photoreceptor inner segment	IEA Inferred from Electronic Annotation more info
is_active_in photoreceptor ribbon synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in presynapse	IEA Inferred from Electronic Annotation more info
located_in presynapse	ISO Inferred from Sequence Orthology more info
located_in presynapse	ISS Inferred from Sequence or Structural Similarity more info
is_active_in presynaptic endocytic zone membrane	IDA Inferred from Direct Assay more info	PubMed
located_in presynaptic endocytic zone membrane	IEA Inferred from Electronic Annotation more info
is_active_in presynaptic endocytic zone membrane	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info
located_in synapse	IEA Inferred from Electronic Annotation more info
located_in synaptic vesicle	ISO Inferred from Sequence Orthology more info
located_in varicosity	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: dynamin-1

Names: dynamin I

NP_001288666.1

EC 3.6.5.5

NP_001355608.1

EC 3.6.5.5

NP_034195.2

EC 3.6.5.5

XP_006497712.2

EC 3.6.5.5

XP_006497713.2

EC 3.6.5.5

XP_006497716.2

EC 3.6.5.5

XP_006497717.2

EC 3.6.5.5

XP_006497718.2

EC 3.6.5.5

XP_006497721.2

EC 3.6.5.5

XP_006497722.2

EC 3.6.5.5

XP_006497723.2

EC 3.6.5.5

XP_006497724.2

EC 3.6.5.5

XP_006497725.1

EC 3.6.5.5

XP_017170817.1

EC 3.6.5.5

XP_036013974.1

EC 3.6.5.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001301737.1 → NP_001288666.1 dynamin-1 isoform 2

See identical proteins and their annotated locations for NP_001288666.1

Status: REVIEWED

Description

Transcript Variant: This variant (2) has multiple differences in the coding region, one of which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. This variant contains the alternate "a" exon in the central coding region and the "b" splicing pattern in the 3' coding region (PMID:10398046, PMID:20700442).

Source sequence(s)

AK011651, AL808027, BC034679, BQ179370, BY297150, CA328097, CO425806

Consensus CDS

CCDS79772.1

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Related

ENSMUSP00000077461.6, ENSMUST00000078352.12

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03378
Location:752 → 844

PHA03378; EBNA-3B; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:657 → 745

GED; Dynamin GTPase effector domain
NM_001368679.1 → NP_001355608.1 dynamin-1 isoform 3

Status: REVIEWED

Description

Transcript Variant: This variant (4) contains two alternate exons in the mid-coding region and uses an alternate acceptor splice site at the 3' terminal exon compared to variant one. The resulting isoform (3) is longer than isoform 1.

Source sequence(s)

AL808027

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03378
Location:752 → 863

PHA03378; EBNA-3B; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:656 → 745

GED; Dynamin GTPase effector domain
NM_010065.3 → NP_034195.2 dynamin-1 isoform 1

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). This variant contains the alternate "b" exon in the central coding region and the "a" splicing pattern in the 3' coding region (PMID:10398046, PMID:20700442).

Source sequence(s)

AA387428, AI894003, AK011651, BC058623, BE860433, BM950315, BY297150, CX239206

Consensus CDS

CCDS38102.1

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Related

ENSMUSP00000088618.6, ENSMUST00000091089.12

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

cd01256
Location:514 → 625

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 501

Dynamin_M; Dynamin central region

pfam02212
Location:653 → 741

GED; Dynamin GTPase effector domain

cl26464
Location:743 → 860

Atrophin-1; Atrophin-1 family

RNA

NR_125959.1 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (3) contains two alternate exons in the central region and uses an alternate splice site in the 3' terminal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). This variant contains the alternate "b" exon in the central region (PMID:20700442).

Source sequence(s)

BC034679, BY297150

Related

ENSMUST00000139624.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000068.8 Reference GRCm39 C57BL/6J

Range

32198483..32243361 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006497654.4 → XP_006497717.2 dynamin-1 isoform X4

See identical proteins and their annotated locations for XP_006497717.2

UniProtKB/TrEMBL

A0A0J9YUE9, A0A0J9YUN4

Related

ENSMUSP00000144264.2, ENSMUST00000201433.4

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03247
Location:747 → 844

PHA03247; large tegument protein UL36; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:657 → 745

GED; Dynamin GTPase effector domain
XM_006497649.3 → XP_006497712.2 dynamin-1 isoform X1

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03247
Location:747 → 864

PHA03247; large tegument protein UL36; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:656 → 745

GED; Dynamin GTPase effector domain
XM_006497659.4 → XP_006497722.2 dynamin-1 isoform X7

See identical proteins and their annotated locations for XP_006497722.2

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03378
Location:752 → 844

PHA03378; EBNA-3B; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:657 → 745

GED; Dynamin GTPase effector domain
XM_006497655.4 → XP_006497718.2 dynamin-1 isoform X5

UniProtKB/TrEMBL

A0A0J9YUE9

Related

ENSMUSP00000108992.2, ENSMUST00000113365.8

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03247
Location:747 → 844

PHA03247; large tegument protein UL36; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:657 → 745

GED; Dynamin GTPase effector domain
XM_036158081.1 → XP_036013974.1 dynamin-1 isoform X3

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03378
Location:752 → 863

PHA03378; EBNA-3B; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:657 → 745

GED; Dynamin GTPase effector domain
XM_006497661.3 → XP_006497724.2 dynamin-1 isoform X8

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Related

ENSMUSP00000108977.2, ENSMUST00000113350.8

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03378
Location:752 → 844

PHA03378; EBNA-3B; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:657 → 745

GED; Dynamin GTPase effector domain
XM_006497653.4 → XP_006497716.2 dynamin-1 isoform X6

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03247
Location:743 → 860

PHA03247; large tegument protein UL36; Provisional

cd01256
Location:514 → 625

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:652 → 741

GED; Dynamin GTPase effector domain
XM_006497658.4 → XP_006497721.2 dynamin-1 isoform X7

See identical proteins and their annotated locations for XP_006497721.2

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Related

ENSMUSP00000143955.2, ENSMUST00000202578.4

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03378
Location:752 → 844

PHA03378; EBNA-3B; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:657 → 745

GED; Dynamin GTPase effector domain
XM_006497650.4 → XP_006497713.2 dynamin-1 isoform X2

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03247
Location:747 → 864

PHA03247; large tegument protein UL36; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:656 → 745

GED; Dynamin GTPase effector domain
XM_017315328.2 → XP_017170817.1 dynamin-1 isoform X8

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Related

ENSMUSP00000108979.3, ENSMUST00000113352.9

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03378
Location:752 → 844

PHA03378; EBNA-3B; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:657 → 745

GED; Dynamin GTPase effector domain
XM_006497662.3 → XP_006497725.1 dynamin-1 isoform X9

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Conserved Domains (5) summary

cd08771
Location:100 → 340

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

PHA03247
Location:793 → 910

PHA03247; large tegument protein UL36; Provisional

cd01256
Location:566 → 675

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:262 → 548

Dynamin_M; Dynamin central region

pfam02212
Location:702 → 791

GED; Dynamin GTPase effector domain
XM_006497660.3 → XP_006497723.2 dynamin-1 isoform X7

See identical proteins and their annotated locations for XP_006497723.2

UniProtKB/Swiss-Prot

A2AN50, A2AN51, A2AN54, A2AN55, P39053, Q3UNM1, Q5DTN7, Q61358, Q61359, Q61360, Q6PDM5, Q8JZZ4, Q9CSY7, Q9QXX1

Conserved Domains (5) summary

smart00053
Location:6 → 245

DYNc; Dynamin, GTPase

PHA03378
Location:752 → 844

PHA03378; EBNA-3B; Provisional

cd01256
Location:520 → 629

PH_dynamin; Dynamin pleckstrin homology (PH) domain

pfam01031
Location:216 → 502

Dynamin_M; Dynamin central region

pfam02212
Location:657 → 745

GED; Dynamin GTPase effector domain