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TMEM174 transmembrane protein 174 [ Homo sapiens (human) ]

Gene ID: 134288, updated on 23-Nov-2021

Summary

Official Symbol
TMEM174provided by HGNC
Official Full Name
transmembrane protein 174provided by HGNC
Primary source
HGNC:HGNC:28187
See related
Ensembl:ENSG00000164325 MIM:614909
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward kidney (RPKM 66.3) See more
Orthologs
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Genomic context

See TMEM174 in Genome Data Viewer
Location:
5q13.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (73173193..73175143)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (72469020..72470970)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379030 Neighboring gene 40S ribosomal protein S3 pseudogene Neighboring gene uncharacterized LOC340090 Neighboring gene uncharacterized LOC105379031

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ31268, MGC13034

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153217.3NP_694949.1  transmembrane protein 174

    See identical proteins and their annotated locations for NP_694949.1

    Status: VALIDATED

    Source sequence(s)
    AC116345, AK315460
    Consensus CDS
    CCDS4018.1
    UniProtKB/Swiss-Prot
    Q8WUU8
    UniProtKB/TrEMBL
    A0A024RAN0
    Related
    ENSP00000296776.5, ENST00000296776.6
    Conserved Domains (1) summary
    pfam15029
    Location:9241
    TMEM174; Transmembrane protein 174

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    73173193..73175143
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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