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IQCF1 IQ motif containing F1 [ Homo sapiens (human) ]

Gene ID: 132141, updated on 23-Nov-2021

Summary

Official Symbol
IQCF1provided by HGNC
Official Full Name
IQ motif containing F1provided by HGNC
Primary source
HGNC:HGNC:28607
See related
Ensembl:ENSG00000173389
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward testis (RPKM 24.8) See more
Orthologs
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Genomic context

See IQCF1 in Genome Data Viewer
Location:
3p21.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (51894876..51903353, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (51928892..51937369, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 504, pseudogene Neighboring gene IQCF5 antisense RNA 1 Neighboring gene IQ motif containing F5 Neighboring gene ribosomal RNA processing 9, U3 small nucleolar RNA binding protein Neighboring gene poly(ADP-ribose) polymerase family member 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ27508, MGC39725

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables calmodulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of acrosome reaction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of acrosome reaction ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of flagellated sperm motility involved in capacitation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in acrosomal vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in acrosomal vesicle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
IQ domain-containing protein F1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152397.3NP_689610.2  IQ domain-containing protein F1

    See identical proteins and their annotated locations for NP_689610.2

    Status: VALIDATED

    Source sequence(s)
    AC097636, BC029595
    Consensus CDS
    CCDS2836.1
    UniProtKB/Swiss-Prot
    Q8N6M8
    Related
    ENSP00000307958.5, ENST00000310914.10
    Conserved Domains (1) summary
    pfam11374
    Location:86143
    DUF3176; Protein of unknown function (DUF3176)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    51894876..51903353 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017005729.1XP_016861218.1  IQ domain-containing protein F1 isoform X1

    Conserved Domains (1) summary
    pfam11374
    Location:51108
    DUF3176; Protein of unknown function (DUF3176)
  2. XM_011533366.2XP_011531668.1  IQ domain-containing protein F1 isoform X2

    See identical proteins and their annotated locations for XP_011531668.1

    Conserved Domains (1) summary
    pfam11374
    Location:51108
    DUF3176; Protein of unknown function (DUF3176)
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