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Dbp D site albumin promoter binding protein [ Mus musculus (house mouse) ]

Gene ID: 13170, updated on 17-Sep-2019

Summary

Official Symbol
Dbpprovided by MGI
Official Full Name
D site albumin promoter binding proteinprovided by MGI
Primary source
MGI:MGI:94866
See related
Ensembl:ENSMUSG00000059824
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
The protein encoded by this gene is a member of the Par bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, Cyp2a4, and Cyp2a5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythym genes. [provided by RefSeq, Feb 2014]
Expression
Biased expression in adrenal adult (RPKM 215.0), bladder adult (RPKM 83.9) and 10 other tissues See more
Orthologs

Genomic context

See Dbp in Genome Data Viewer
Location:
7 B3; 7 29.45 cM
Exon count:
4
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (45705100..45710203)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (52960617..52965573)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene secretory blood group 1 Neighboring gene netrin 5 Neighboring gene carbonic anhydrase 11 Neighboring gene sphingosine kinase 2 Neighboring gene ribosomal protein L18 Neighboring gene family with sequence similarity 83, member E Neighboring gene sperm acrosome associated 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
circadian rhythm TAS
Traceable Author Statement
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
rhythmic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
D site-binding protein
Names
albumin D box-binding protein
albumin D-element-binding protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016974.3NP_058670.2  D site-binding protein

    See identical proteins and their annotated locations for NP_058670.2

    Status: VALIDATED

    Source sequence(s)
    AC167242, AK140243
    Consensus CDS
    CCDS21260.1
    UniProtKB/Swiss-Prot
    Q60925
    UniProtKB/TrEMBL
    Q3USN7
    Related
    ENSMUSP00000079693.3, ENSMUST00000080885.11
    Conserved Domains (1) summary
    cd14695
    Location:254313
    bZIP_HLF; Basic leucine zipper (bZIP) domain of Hepatic leukemia factor (HLF) and similar proteins: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p6 C57BL/6J

    Range
    45705100..45710203
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006540596.3XP_006540659.1  D site-binding protein isoform X1

    See identical proteins and their annotated locations for XP_006540659.1

    UniProtKB/TrEMBL
    A0A1B0GS46
    Related
    ENSMUSP00000147790.1, ENSMUST00000211513.1
    Conserved Domains (1) summary
    cd14695
    Location:117176
    bZIP_HLF; Basic leucine zipper (bZIP) domain of Hepatic leukemia factor (HLF) and similar proteins: a DNA-binding and dimerization domain
  2. XM_006540597.2XP_006540660.1  D site-binding protein isoform X2

    Conserved Domains (1) summary
    cd14695
    Location:117176
    bZIP_HLF; Basic leucine zipper (bZIP) domain of Hepatic leukemia factor (HLF) and similar proteins: a DNA-binding and dimerization domain
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