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Cyp51 cytochrome P450, family 51 [ Mus musculus (house mouse) ]

Gene ID: 13121, updated on 23-May-2018
Official Symbol
Cyp51provided by MGI
Official Full Name
cytochrome P450, family 51provided by MGI
Primary source
MGI:MGI:106040
See related
Ensembl:ENSMUSG00000001467 Vega:OTTMUSG00000022725
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ldm; CYPLI; P450LI; Cyp51a1; AI426508; P450-14DM
Expression
Ubiquitous expression in CNS E18 (RPKM 27.0), CNS E11.5 (RPKM 23.5) and 27 other tissues See more
Orthologs
See Cyp51 in Genome Data Viewer
Location:
5 A1; 5 2.3 cM
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (4080674..4104697, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (4080674..4104697, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene A kinase (PRKA) anchor protein (yotiao) 9 Neighboring gene Wdr46 retrotransposed pseudogene Neighboring gene predicted gene, 40260 Neighboring gene mitochondrial transcription termination factor 1b Neighboring gene predicted gene, 40261

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
heme binding ISO
Inferred from Sequence Orthology
more info
 
iron ion binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 
sterol 14-demethylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sterol 14-demethylase activity ISO
Inferred from Sequence Orthology
more info
 
sterol 14-demethylase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
cholesterol biosynthetic process TAS
Traceable Author Statement
more info
PubMed 
cholesterol biosynthetic process via 24,25-dihydrolanosterol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cholesterol biosynthetic process via 24,25-dihydrolanosterol ISO
Inferred from Sequence Orthology
more info
 
cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
steroid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
steroid metabolic process IEA
Inferred from Electronic Annotation
more info
 
sterol biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
sterol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Preferred Names
lanosterol 14-alpha demethylase
Names
cytochrome P450 51A1
cytochrome P450, 51
cytochrome P450-14DM
cytochrome P45014DM
cytochrome P450LI
sterol 14-alpha demethylase
NP_064394.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020010.2NP_064394.2  lanosterol 14-alpha demethylase

    See identical proteins and their annotated locations for NP_064394.2

    Status: VALIDATED

    Source sequence(s)
    AC064793, AC068609, AK028815, CB524876
    Consensus CDS
    CCDS19071.1
    UniProtKB/Swiss-Prot
    Q8K0C4
    Related
    ENSMUSP00000001507.4, OTTMUSP00000026030, ENSMUST00000001507.4, OTTMUST00000054505
    Conserved Domains (1) summary
    cl12078
    Location:67477
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

    Range
    4080674..4104697 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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