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FAM3D family with sequence similarity 3 member D [ Homo sapiens (human) ]

Gene ID: 131177, updated on 12-Aug-2018

Summary

Official Symbol
FAM3Dprovided by HGNC
Official Full Name
family with sequence similarity 3 member Dprovided by HGNC
Primary source
HGNC:HGNC:18665
See related
Ensembl:ENSG00000198643 MIM:608619; Vega:OTTHUMG00000159148
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EF7; OIT1
Expression
Biased expression in colon (RPKM 146.4), salivary gland (RPKM 60.2) and 6 other tissues See more
Orthologs

Genomic context

See FAM3D in Genome Data Viewer
Location:
3p14.2
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 3 NC_000003.12 (58633943..58666843, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (58619670..58652575, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984079 Neighboring gene ribosomal protein L27 pseudogene 9 Neighboring gene acyl-CoA oxidase 2 Neighboring gene family with sequence similarity 107 member A Neighboring gene FAM3D antisense RNA 1 Neighboring gene uncharacterized LOC105377109 Neighboring gene chromosome 3 open reading frame 67 Neighboring gene C3orf67 antisense RNA 1 Neighboring gene uncharacterized LOC105377110 Neighboring gene small nuclear ribonucleoprotein polypeptide B2 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
cytokine activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
negative regulation of glucagon secretion IEA
Inferred from Electronic Annotation
more info
 
negative regulation of insulin secretion IDA
Inferred from Direct Assay
more info
PubMed 
regulation of signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular region NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
protein FAM3D
Names
Oncoprotein-induced transcript 1
cytokine-like protein EF-7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138805.2NP_620160.1  protein FAM3D precursor

    See identical proteins and their annotated locations for NP_620160.1

    Status: VALIDATED

    Source sequence(s)
    AW662283, AY358677, CA314533
    Consensus CDS
    CCDS2893.1
    UniProtKB/Swiss-Prot
    Q96BQ1
    UniProtKB/TrEMBL
    A0A0A8K9B4
    Related
    ENSP00000351632.2, OTTHUMP00000214165, ENST00000358781.6, OTTHUMT00000353494
    Conserved Domains (1) summary
    cd13940
    Location:50220
    ILEI_FAM3C; Interleukin-like EMT inducer

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p12 Primary Assembly

    Range
    58633943..58666843 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005264863.4XP_005264920.1  protein FAM3D isoform X4

    See identical proteins and their annotated locations for XP_005264920.1

    Conserved Domains (1) summary
    cd13940
    Location:49219
    ILEI_FAM3C; Interleukin-like EMT inducer
  2. XM_011533350.2XP_011531652.1  protein FAM3D isoform X2

    Conserved Domains (1) summary
    cd13940
    Location:55225
    ILEI_FAM3C; Interleukin-like EMT inducer
  3. XM_011533348.2XP_011531650.1  protein FAM3D isoform X1

    See identical proteins and their annotated locations for XP_011531650.1

    Conserved Domains (1) summary
    cd13940
    Location:56226
    ILEI_FAM3C; Interleukin-like EMT inducer
  4. XM_006712967.3XP_006713030.1  protein FAM3D isoform X6

    See identical proteins and their annotated locations for XP_006713030.1

    Conserved Domains (1) summary
    cd13940
    Location:13183
    ILEI_FAM3C; Interleukin-like EMT inducer
  5. XM_011533352.2XP_011531654.1  protein FAM3D isoform X5

    See identical proteins and their annotated locations for XP_011531654.1

    Conserved Domains (1) summary
    cd13940
    Location:14184
    ILEI_FAM3C; Interleukin-like EMT inducer
  6. XM_005264864.4XP_005264921.1  protein FAM3D isoform X4

    See identical proteins and their annotated locations for XP_005264921.1

    Conserved Domains (1) summary
    cd13940
    Location:49219
    ILEI_FAM3C; Interleukin-like EMT inducer
  7. XM_005264862.4XP_005264919.1  protein FAM3D isoform X3

    See identical proteins and their annotated locations for XP_005264919.1

    UniProtKB/Swiss-Prot
    Q96BQ1
    UniProtKB/TrEMBL
    A0A0A8K9B4
    Conserved Domains (1) summary
    cd13940
    Location:50220
    ILEI_FAM3C; Interleukin-like EMT inducer
  8. XM_011533354.2XP_011531656.1  protein FAM3D isoform X6

    See identical proteins and their annotated locations for XP_011531656.1

    Conserved Domains (1) summary
    cd13940
    Location:13183
    ILEI_FAM3C; Interleukin-like EMT inducer
  9. XM_011533353.2XP_011531655.1  protein FAM3D isoform X5

    See identical proteins and their annotated locations for XP_011531655.1

    Conserved Domains (1) summary
    cd13940
    Location:14184
    ILEI_FAM3C; Interleukin-like EMT inducer
  10. XM_011533349.3XP_011531651.1  protein FAM3D isoform X1

    See identical proteins and their annotated locations for XP_011531651.1

    Conserved Domains (1) summary
    cd13940
    Location:56226
    ILEI_FAM3C; Interleukin-like EMT inducer
  11. XM_011533351.2XP_011531653.1  protein FAM3D isoform X3

    See identical proteins and their annotated locations for XP_011531653.1

    UniProtKB/Swiss-Prot
    Q96BQ1
    UniProtKB/TrEMBL
    A0A0A8K9B4
    Conserved Domains (1) summary
    cd13940
    Location:50220
    ILEI_FAM3C; Interleukin-like EMT inducer
  12. XM_006712965.3XP_006713028.1  protein FAM3D isoform X3

    See identical proteins and their annotated locations for XP_006713028.1

    UniProtKB/Swiss-Prot
    Q96BQ1
    UniProtKB/TrEMBL
    A0A0A8K9B4
    Conserved Domains (1) summary
    cd13940
    Location:50220
    ILEI_FAM3C; Interleukin-like EMT inducer
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