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LOC130067627 ATAC-STARR-seq lymphoblastoid silent region 13854 [ Homo sapiens (human) ]

Gene ID: 130067627, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130067627
Gene description
ATAC-STARR-seq lymphoblastoid silent region 13854
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as a silencer based on its ability to repress an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130067627 in Genome Data Viewer
Location:
chromosome: 22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (43111400..43111619)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (43592566..43592785)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (43507406..43507625)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene TTLL1 antisense RNA 1 Neighboring gene TTL family tubulin polyglutamylase complex subunit L1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43474531-43475053 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43475054-43475575 Neighboring gene Sharpr-MPRA regulatory region 1995 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13852 Neighboring gene ribosomal protein S25 pseudogene 10 Neighboring gene Sharpr-MPRA regulatory region 7153 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:43506823-43507381 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19183 Neighboring gene BCL2 interacting killer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43524576-43525453 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_63425 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13855 Neighboring gene malonyl-CoA-acyl carrier protein transacylase Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19185 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13856 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19186 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43553089-43553609 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43559052-43559555 Neighboring gene translocator protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_202042.1 

    Range
    101..320
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    43111400..43111619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    43592566..43592785
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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