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Hapln1 hyaluronan and proteoglycan link protein 1 [ Mus musculus (house mouse) ]

Gene ID: 12950, updated on 3-Oct-2018

Summary

Official Symbol
Hapln1provided by MGI
Official Full Name
hyaluronan and proteoglycan link protein 1provided by MGI
Primary source
MGI:MGI:1337006
See related
Ensembl:ENSMUSG00000021613
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LP; CLP; LP-1; Crtl1; Crtl1l; BB099155
Expression
Biased expression in limb E14.5 (RPKM 38.8), CNS E14 (RPKM 5.4) and 4 other tissues See more
Orthologs

Genomic context

See Hapln1 in Genome Data Viewer
Location:
13 C3; 13 45.5 cM
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (89540528..89611832)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (89680241..89751437)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene EGF-like repeats and discoidin I-like domains 3 Neighboring gene predicted gene, 46433 Neighboring gene predicted gene, 34699 Neighboring gene acylglycerol kinase pseudogene Neighboring gene high mobility group box 1 pseudogene Neighboring gene versican Neighboring gene uncharacterized LOC108168105 Neighboring gene predicted gene 4117

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
central nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
collagen-containing extracellular matrix HDA PubMed 
extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular matrix IDA
Inferred from Direct Assay
more info
PubMed 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
synapse EXP
Inferred from Experiment
more info
PubMed 
synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
hyaluronan and proteoglycan link protein 1
Names
cartilage link protein 1
cartilage-link protein
cartilage-linking protein 1
link protein
proteoglycan link protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013500.4NP_038528.3  hyaluronan and proteoglycan link protein 1 precursor

    See identical proteins and their annotated locations for NP_038528.3

    Status: VALIDATED

    Source sequence(s)
    AC154460, AK032750
    Consensus CDS
    CCDS26671.1
    UniProtKB/Swiss-Prot
    Q9QUP5
    Related
    ENSMUSP00000022108.7, ENSMUST00000022108.8
    Conserved Domains (4) summary
    cd05877
    Location:55162
    Ig_LP_like; Immunoglobulin (Ig)-like domain of human cartilage link protein (LP)
    smart00410
    Location:56157
    IG_like; Immunoglobulin like
    cd03518
    Location:161255
    Link_domain_HAPLN_module_1; Link_domain_HAPLN_module_1; this link domain is found in the first link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding ...
    cd03519
    Location:262352
    Link_domain_HAPLN_module_2; Link_domain_HAPLN_module_2; this link domain is found in the second link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

    Range
    89540528..89611832
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517075.3XP_006517138.1  hyaluronan and proteoglycan link protein 1 isoform X1

    Conserved Domains (4) summary
    cd05877
    Location:54161
    Ig_LP_like; Immunoglobulin (Ig)-like domain of human cartilage link protein (LP)
    smart00410
    Location:55156
    IG_like; Immunoglobulin like
    cd03518
    Location:160254
    Link_domain_HAPLN_module_1; Link_domain_HAPLN_module_1; this link domain is found in the first link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding ...
    cd03519
    Location:261351
    Link_domain_HAPLN_module_2; Link_domain_HAPLN_module_2; this link domain is found in the second link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a ...
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