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Cpt1b carnitine palmitoyltransferase 1b, muscle [ Mus musculus (house mouse) ]

Gene ID: 12895, updated on 21-May-2024

Summary

Official Symbol
Cpt1bprovided by MGI
Official Full Name
carnitine palmitoyltransferase 1b, muscleprovided by MGI
Primary source
MGI:MGI:1098297
See related
Ensembl:ENSMUSG00000078937 AllianceGenome:MGI:1098297
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cpt1; Cpti; Cpt1-m; Cpti-m; M-cpti
Summary
Predicted to enable carnitine O-palmitoyltransferase activity. Involved in response to blue light. Located in mitochondrion. Is expressed in cardiovascular system; early conceptus; and ovary. Orthologous to human CPT1B (carnitine palmitoyltransferase 1B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in heart adult (RPKM 181.3), testis adult (RPKM 117.6) and 6 other tissues See more
Orthologs
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Genomic context

See Cpt1b in Genome Data Viewer
Location:
15 E3; 15 44.89 cM
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (89300608..89310065, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (89416405..89425862, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene kelch domain containing 7B Neighboring gene synaptonemal complex central element protein 3 Neighboring gene predicted readthrough transcript (NMD candidate), 44502 Neighboring gene RIKEN cDNA C730034F03 gene Neighboring gene STARR-positive B cell enhancer ABC_E7406 Neighboring gene STARR-positive B cell enhancer ABC_E9159 Neighboring gene choline kinase beta

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (3)  1 citation

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough Gm44502

Readthrough gene: Gm44502, Included gene: Chkb

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables carnitine O-palmitoyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables carnitine O-palmitoyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables carnitine O-palmitoyltransferase activity TAS
Traceable Author Statement
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carnitine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in carnitine metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in fatty acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in long-chain fatty acid transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in long-chain fatty acid transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within long-chain fatty acid transport TAS
Traceable Author Statement
more info
PubMed 
involved_in response to blue light IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial outer membrane TAS
Traceable Author Statement
more info
PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
carnitine O-palmitoyltransferase 1, muscle isoform
Names
muscle-type carnitine palmitoyltransferase I
NP_034078.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009948.2NP_034078.2  carnitine O-palmitoyltransferase 1, muscle isoform

    See identical proteins and their annotated locations for NP_034078.2

    Status: VALIDATED

    Source sequence(s)
    AK029141, CJ092541, CJ238532
    Consensus CDS
    CCDS27749.1
    UniProtKB/Swiss-Prot
    O35287, Q924X2, Q9QYP4
    UniProtKB/TrEMBL
    Q3UIM5
    Related
    ENSMUSP00000104936.3, ENSMUST00000109313.9
    Conserved Domains (2) summary
    pfam00755
    Location:173761
    Carn_acyltransf; Choline/Carnitine o-acyltransferase
    pfam16484
    Location:146
    CPT_N; Carnitine O-palmitoyltransferase N-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    89300608..89310065 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)