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SIRPD signal regulatory protein delta [ Homo sapiens (human) ]

Gene ID: 128646, updated on 5-Jan-2022

Summary

Official Symbol
SIRPDprovided by HGNC
Official Full Name
signal regulatory protein deltaprovided by HGNC
Primary source
HGNC:HGNC:16248
See related
Ensembl:ENSG00000125900
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PTPNS1L2; dJ576H24.4
Summary
Predicted to be located in extracellular region. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Restricted expression toward testis (RPKM 26.7) See more
Orthologs
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Genomic context

See SIRPD in Genome Data Viewer
Location:
20p13
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 20 NC_000020.11 (1534251..1557705, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (1514897..1538351, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372499 Neighboring gene uncharacterized LOC105372498 Neighboring gene RNA, U6 small nuclear 917, pseudogene Neighboring gene uncharacterized LOC107985409 Neighboring gene signal regulatory protein beta 1 Neighboring gene SIRPG antisense RNA 1 Neighboring gene signal regulatory protein gamma

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
signal-regulatory protein delta
Names
SIRP-delta
protein tyrosine phosphatase, non-receptor type substrate 1-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178460.3NP_848555.2  signal-regulatory protein delta precursor

    See identical proteins and their annotated locations for NP_848555.2

    Status: VALIDATED

    Source sequence(s)
    AL049634, BC033502, DA466740
    Consensus CDS
    CCDS13018.1
    UniProtKB/Swiss-Prot
    Q9H106
    Related
    ENSP00000371036.3, ENST00000381623.4
    Conserved Domains (2) summary
    smart00410
    Location:38118
    IG_like; Immunoglobulin like
    pfam07686
    Location:34140
    V-set; Immunoglobulin V-set domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    1534251..1557705 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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