U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SNHG11 small nucleolar RNA host gene 11 [ Homo sapiens (human) ]

Gene ID: 128439, updated on 4-Mar-2025

Summary

Go to the top of the page Help
Official Symbol
SNHG11provided by HGNC
Official Full Name
small nucleolar RNA host gene 11provided by HGNC
Primary source
HGNC:HGNC:25046
See related
Ensembl:ENSG00000174365 MIM:619494; AllianceGenome:HGNC:25046
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C20orf198; LINC00101; NCRNA00101
Summary
This gene is a member of the non-protein-coding multiple snoRNA host gene family. Two snoRNAs are derived from the introns of this host gene. Although many alternative splice variants have been observed, the gene is thought to have no protein-coding potential. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in testis (RPKM 6.8), prostate (RPKM 5.3) and 25 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SNHG11 in Genome Data Viewer
Location:
20q11.23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (38446654..38450921)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (40174250..40178518)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (37075297..37079564)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904958 Neighboring gene small nucleolar RNA host gene 17 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17857 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17858 Neighboring gene small nucleolar RNA SNORA71 Neighboring gene small nucleolar RNA, H/ACA box 71D Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17859 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:37076132-37076686 Neighboring gene small nucleolar RNA, H/ACA box 71E Neighboring gene small nucleolar RNA, H/ACA box 60 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12899 Neighboring gene Ral GTPase activating protein non-catalytic subunit beta Neighboring gene microRNA 548o-2 Neighboring gene ribosomal protein S3 pseudogene 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The function of long non-coding RNA SNHG11 and its working mechanism in triple-negative breast cancer. Al-Hazani TMI, et al. Pathol Res Pract, 2023 Aug. PMID 37320865
  2. SNHG11: A New Budding Star in Tumors and Inflammatory Diseases. Wu Y. Mini Rev Med Chem, 2023. PMID 37165588
  3. Prostate cancer risk SNP rs10993994 is a trans-eQTL for SNHG11 mediated through MSMB. Bicak M, et al. Hum Mol Genet, 2020 Jun 27. PMID 32065238, Free PMC Article
  4. LncRNA SNHG11 accelerates the progression of lung adenocarcinoma via activating Notch pathways. Deng Y, et al. Pathol Res Pract, 2022 Jun. PMID 35487027
  5. LncRNA SNHG11 enhances bevacizumab resistance in colorectal cancer by mediating miR-1207-5p/ABCC1 axis. Huang W, et al. Anticancer Drugs, 2022 Jul 1. PMID 35324517

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The lncRNA Snhg11, a new candidate contributing to neurogenesis, plasticity, and memory deficits in Down syndrome.
    Title: The lncRNA Snhg11, a new candidate contributing to neurogenesis, plasticity, and memory deficits in Down syndrome.
  2. [LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/Akt/mTOR signaling pathway].
    Title: [LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/Akt/mTOR signaling pathway].
  3. SNHG11: A New Budding Star in Tumors and Inflammatory Diseases.
    Title: SNHG11: A New Budding Star in Tumors and Inflammatory Diseases.
  4. The function of long non-coding RNA SNHG11 and its working mechanism in triple-negative breast cancer.
    Title: The function of long non-coding RNA SNHG11 and its working mechanism in triple-negative breast cancer.
  5. Long non-coding RNA SNHG11 regulates the Wnt/beta-catenin signaling pathway through rho/ROCK in trabecular meshwork cells.
    Title: Long non-coding RNA SNHG11 regulates the Wnt/β-catenin signaling pathway through rho/ROCK in trabecular meshwork cells.
  6. lncRNA SNHG11 promotes the development of colorectal cancer by mediating miR-339-3p/SHOX2.
    Title: lncRNA SNHG11 promotes the development of colorectal cancer by mediating miR-339-3p/SHOX2.
  7. LncRNA SNHG11 accelerates the progression of lung adenocarcinoma via activating Notch pathways.
    Title: LncRNA SNHG11 accelerates the progression of lung adenocarcinoma via activating Notch pathways.
  8. LncRNA SNHG11 enhances bevacizumab resistance in colorectal cancer by mediating miR-1207-5p/ABCC1 axis.
    Title: LncRNA SNHG11 enhances bevacizumab resistance in colorectal cancer by mediating miR-1207-5p/ABCC1 axis.
  9. Prognostic Value of Long Noncoding RNA SNHG11 in Patients with Prostate Cancer.
    Title: Prognostic Value of Long Noncoding RNA SNHG11 in Patients with Prostate Cancer.
  10. Exosome-mediated lncRNA SNHG11 regulates angiogenesis in pancreatic carcinoma through miR-324-3p/VEGFA axis.
    Title: Exosome-mediated lncRNA SNHG11 regulates angiogenesis in pancreatic carcinoma through miR-324-3p/VEGFA axis.
Submit: New GeneRIF Correction See all GeneRIFs (20)

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Other Names

  • long intergenic non-protein coding RNA 101
  • small nucleolar RNA host gene (non-protein coding) 11
  • small nucleolar RNA host gene 11 (non-protein coding)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003239.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AF454939, AF497716, AK055434
    Related
    ENST00000656815.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    38446654..38450921
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    40174250..40178518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_139016.2: Suppressed sequence

    Description
    NM_139016.2: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials