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UBXN10 UBX domain protein 10 [ Homo sapiens (human) ]

Gene ID: 127733, updated on 27-Nov-2024

Summary

Official Symbol
UBXN10provided by HGNC
Official Full Name
UBX domain protein 10provided by HGNC
Primary source
HGNC:HGNC:26354
See related
Ensembl:ENSG00000162543 MIM:616783; AllianceGenome:HGNC:26354
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UBXD3
Summary
Predicted to enable ubiquitin binding activity. Involved in cilium assembly. Located in cilium and intraciliary transport particle B. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in testis (RPKM 9.4), lung (RPKM 3.6) and 16 other tissues See more
Orthologs
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Genomic context

See UBXN10 in Genome Data Viewer
Location:
1p36.12
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (20183331..20196050)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (20006726..20019694)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (20512589..20522543)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:20468424-20468924 Neighboring gene phospholipase A2 group IIF Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:20474795-20475295 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:20476004-20476630 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:20479806-20480357 Neighboring gene uncharacterized LOC117779438 Neighboring gene phospholipase A2 group IIC Neighboring gene ATAC-STARR-seq lymphoblastoid active region 316 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:20511679-20512878 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 317 Neighboring gene uncharacterized LOC105376825 Neighboring gene uncharacterized LOC105376826 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:20537509-20538708

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ25429

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cilium assembly IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cilium IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of intraciliary transport particle B IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
UBX domain-containing protein 10
Names
UBX domain containing 3
UBX domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152376.5NP_689589.1  UBX domain-containing protein 10

    See identical proteins and their annotated locations for NP_689589.1

    Status: VALIDATED

    Source sequence(s)
    BX648631, Z98257
    Consensus CDS
    CCDS205.1
    UniProtKB/Swiss-Prot
    Q5R386, Q96LJ8
    Related
    ENSP00000364240.3, ENST00000375099.4
    Conserved Domains (1) summary
    cl25424
    Location:196269
    TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    20183331..20196050
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011540699.4XP_011539001.1  UBX domain-containing protein 10 isoform X1

    See identical proteins and their annotated locations for XP_011539001.1

    UniProtKB/Swiss-Prot
    Q5R386, Q96LJ8
    Conserved Domains (1) summary
    cl25424
    Location:196269
    TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...
  2. XM_005245742.5XP_005245799.1  UBX domain-containing protein 10 isoform X1

    See identical proteins and their annotated locations for XP_005245799.1

    UniProtKB/Swiss-Prot
    Q5R386, Q96LJ8
    Conserved Domains (1) summary
    cl25424
    Location:196269
    TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    20006726..20019694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054334395.1XP_054190370.1  UBX domain-containing protein 10 isoform X1

    UniProtKB/Swiss-Prot
    Q5R386, Q96LJ8
  2. XM_054334396.1XP_054190371.1  UBX domain-containing protein 10 isoform X1

    UniProtKB/Swiss-Prot
    Q5R386, Q96LJ8