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OR2T10 olfactory receptor family 2 subfamily T member 10 [ Homo sapiens (human) ]

Gene ID: 127069, updated on 11-Jun-2021

Summary

Official Symbol
OR2T10provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily T member 10provided by HGNC
Primary source
HGNC:HGNC:19573
See related
Ensembl:ENSG00000184022
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR1-64
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Biased expression in kidney (RPKM 1.3), prostate (RPKM 0.1) and 1 other tissue See more
Orthologs
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Genomic context

See OR2T10 in Genome Data Viewer
Location:
1q44
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (248590487..248597700, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248753788..248761001, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily T member 29 Neighboring gene olfactory receptor family 2 subfamily T member 34 Neighboring gene olfactory receptor family 2 subfamily T member 11 Neighboring gene olfactory receptor family 2 subfamily T member 35

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 2T10
Names
olfactory receptor OR1-64

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004693.2NP_001004693.1  olfactory receptor 2T10

    See identical proteins and their annotated locations for NP_001004693.1

    Status: VALIDATED

    Source sequence(s)
    AC098483
    Consensus CDS
    CCDS31121.1
    UniProtKB/Swiss-Prot
    Q8NGZ9
    UniProtKB/TrEMBL
    A0A126GV79
    Related
    ENSP00000493236.1, ENST00000642090.1
    Conserved Domains (1) summary
    cd15421
    Location:27301
    7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    248590487..248597700 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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