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Cd68 CD68 antigen [ Mus musculus (house mouse) ]

Gene ID: 12514, updated on 17-Nov-2020

Summary

Official Symbol
Cd68provided by MGI
Official Full Name
CD68 antigenprovided by MGI
Primary source
MGI:MGI:88342
See related
Ensembl:ENSMUSG00000018774
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
La; ma; Sca; gp11; Lamp4; gp110; Scard1
Expression
Ubiquitous expression in spleen adult (RPKM 35.5), thymus adult (RPKM 25.5) and 26 other tissues See more
Orthologs

Genomic context

See Cd68 in Genome Data Viewer
Location:
11 B3; 11 42.86 cM
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (69555039..69556996, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (69664213..69666170, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (69477873..69479564, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene SRY (sex determining region Y)-box 15 Neighboring gene mannose-P-dolichol utilization defect 1 Neighboring gene microRNA 1934 Neighboring gene eukaryotic translation initiation factor 4A1 Neighboring gene predicted gene, 24029 Neighboring gene predicted gene, 25835

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
endosome IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
late endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lysosomal membrane RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
lysosome IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291058.1NP_001277987.1  macrosialin precursor

    See identical proteins and their annotated locations for NP_001277987.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.
    Source sequence(s)
    AW123877, BY210951, X68273
    Consensus CDS
    CCDS70216.1
    UniProtKB/Swiss-Prot
    P31996
    Related
    ENSMUSP00000018918.5, ENSMUST00000018918.11
    Conserved Domains (2) summary
    pfam01299
    Location:36326
    Lamp; Lysosome-associated membrane glycoprotein (Lamp)
    pfam05647
    Location:43102
    Epiglycanin_TR; Tandem-repeating region of mucin, epiglycanin-like

RNA

  1. NR_110993.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AW123877, BY207885, BY210951, X68273

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    69555039..69556996 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_009853.1: Suppressed sequence

    Description
    NM_009853.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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