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SLC51B solute carrier family 51 subunit beta [ Homo sapiens (human) ]

Gene ID: 123264, updated on 21-Aug-2021

Summary

Official Symbol
SLC51Bprovided by HGNC
Official Full Name
solute carrier family 51 subunit betaprovided by HGNC
Primary source
HGNC:HGNC:29956
See related
Ensembl:ENSG00000186198 MIM:612085
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OSTB; PBAM2; OSTBETA
Expression
Biased expression in small intestine (RPKM 39.7), duodenum (RPKM 31.2) and 4 other tissues See more
Orthologs
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Genomic context

See SLC51B in Genome Data Viewer
Location:
15q22.31
Exon count:
5
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (65045387..65053397)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (65337725..65345735)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene SPG21 abhydrolase domain containing, maspardin Neighboring gene mitochondrial methionyl-tRNA formyltransferase Neighboring gene transmembrane protein 126A pseudogene Neighboring gene RAS like family 12 Neighboring gene kelch repeat and BTB domain containing 13 Neighboring gene ubiquitin associated protein 1 like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ26090, MGC118959, MGC118960, MGC118961

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables bile acid transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein heterodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in bile acid and bile salt transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in bile acid and bile salt transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in bile acid secretion IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in positive regulation of protein exit from endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of protein glycosylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of protein targeting to membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of protein stability ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in basolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
part_of protein-containing complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of protein-containing complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
organic solute transporter subunit beta
Names
OST-beta
organic solute transporter beta subunit
solute carrier family 51 beta subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178859.4NP_849190.2  organic solute transporter subunit beta

    See identical proteins and their annotated locations for NP_849190.2

    Status: VALIDATED

    Source sequence(s)
    AC013553, AI793107, AK129601
    Consensus CDS
    CCDS10199.1
    UniProtKB/Swiss-Prot
    Q86UW2
    Related
    ENSP00000335292.2, ENST00000334287.3
    Conserved Domains (1) summary
    pfam15048
    Location:3122
    OSTbeta; Organic solute transporter subunit beta protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    65045387..65053397
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005254159.5XP_005254216.1  organic solute transporter subunit beta isoform X1

    See identical proteins and their annotated locations for XP_005254216.1

    UniProtKB/Swiss-Prot
    Q86UW2
    Conserved Domains (1) summary
    pfam15048
    Location:3122
    OSTbeta; Organic solute transporter subunit beta protein
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