Format

Send to:

Choose Destination

SLC51B solute carrier family 51 beta subunit [ Homo sapiens (human) ]

Gene ID: 123264, updated on 6-Sep-2017
Official Symbol
SLC51Bprovided by HGNC
Official Full Name
solute carrier family 51 beta subunitprovided by HGNC
Primary source
HGNC:HGNC:29956
See related
Ensembl:ENSG00000186198 MIM:612085; Vega:OTTHUMG00000133116
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OSTB; OSTBETA
Orthologs
Location:
15q22.31
Exon count:
5
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 15 NC_000015.10 (65045370..65053396)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (65337708..65345734)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene SPG21, maspardin Neighboring gene mitochondrial methionyl-tRNA formyltransferase Neighboring gene transmembrane protein 126A pseudogene Neighboring gene RAS like family 12 Neighboring gene uncharacterized LOC105370862 Neighboring gene kelch repeat and BTB domain containing 13

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Bile secretion, organism-specific biosystem (from KEGG)
    Bile secretion, organism-specific biosystemBile is a vital secretion, essential for digestion and absorption of fats and fat-soluble vitamins in the small intestine. Moreover, bile is an important route of elimination for excess cholesterol a...
  • Bile secretion, conserved biosystem (from KEGG)
    Bile secretion, conserved biosystemBile is a vital secretion, essential for digestion and absorption of fats and fat-soluble vitamins in the small intestine. Moreover, bile is an important route of elimination for excess cholesterol a...
  • Drug Induction of Bile Acid Pathway, organism-specific biosystem (from WikiPathways)
    Drug Induction of Bile Acid Pathway, organism-specific biosystem
    Drug Induction of Bile Acid Pathway

Markers

Homology

Clone Names

  • FLJ26090, MGC118959, MGC118960, MGC118961

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein heterodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
 
transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
bile acid and bile salt transport ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of protein exit from endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of protein glycosylation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of protein targeting to membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of protein stability ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
integral component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
protein complex ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
organic solute transporter subunit beta
Names
OST-beta
organic solute transporter beta subunit
solute carrier family 51 subunit beta

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178859.3NP_849190.2  organic solute transporter subunit beta

    See identical proteins and their annotated locations for NP_849190.2

    Status: VALIDATED

    Source sequence(s)
    AC013553, AI793107, AK129601
    Consensus CDS
    CCDS10199.1
    UniProtKB/Swiss-Prot
    Q86UW2
    Related
    ENSP00000335292.2, OTTHUMP00000164149, ENST00000334287.2, OTTHUMT00000256783
    Conserved Domains (1) summary
    pfam15048
    Location:3122
    OSTbeta; Organic solute transporter subunit beta protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p7 Primary Assembly

    Range
    65045370..65053396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005254159.4XP_005254216.1  organic solute transporter subunit beta isoform X1

    See identical proteins and their annotated locations for XP_005254216.1

    UniProtKB/Swiss-Prot
    Q86UW2
    Conserved Domains (1) summary
    pfam15048
    Location:3122
    OSTbeta; Organic solute transporter subunit beta protein

Alternate CHM1_1.1

Genomic

  1. NC_018926.2 Alternate CHM1_1.1

    Range
    65457493..65465519
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center