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DOT1L DOT1 like histone lysine methyltransferase [ Bufo bufo (common toad) ]

Gene ID: 120989505, updated on 21-Mar-2024

Summary

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Gene symbol
DOT1L
Gene description
DOT1 like histone lysine methyltransferase
Gene type
protein coding
RefSeq status
MODEL
Organism
Bufo bufo
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Neobatrachia; Hyloidea; Bufonidae; Bufo
Orthologs
human mouse all
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Genomic context

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See DOT1L in Genome Data Viewer
Location:
chromosome: 2
Exon count:
28
Annotation release Status Assembly Chr Location
100 current aBufBuf1.1 (GCF_905171765.1) 2 NC_053390.1 (462815450..462959545)

Chromosome 2 - NC_053390.1Genomic Context describing neighboring genes Neighboring gene growth differentiation factor 15 Neighboring gene adaptor related protein complex 3 subunit delta 1 Neighboring gene pleckstrin homology domain containing J1 Neighboring gene splicing factor 3a subunit 2 Neighboring gene anti-Mullerian hormone

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053390.1 Chromosome 2 Reference aBufBuf1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K79 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription regulatory region DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: histone-lysine N-methyltransferase, H3 lysine-79 specific

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bufo bufo Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aBufBuf1.1

Genomic

  1. NC_053390.1 Reference aBufBuf1.1

    Range
    462815450..462959545
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040417653.1 → XP_040273587.1  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase, H3 lysine-79 specific

    Conserved Domains (3) summary
    pfam08123
    Location:115 → 317
    DOT1; Histone methylation protein DOT1
    PHA03247
    Location:350 → 480
    PHA03247; large tegument protein UL36; Provisional
    COG0419
    Location:495 → 665
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
Nucleotide Protein
Heading Accession and Version

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