U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR4B1 olfactory receptor family 4 subfamily B member 1 [ Homo sapiens (human) ]

Gene ID: 119765, updated on 17-Jun-2024

Summary

Official Symbol
OR4B1provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily B member 1provided by HGNC
Primary source
HGNC:HGNC:8290
See related
Ensembl:ENSG00000175619 AllianceGenome:HGNC:8290
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OST208; OR11-106
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR4B1 in Genome Data Viewer
Location:
11p11.2
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (48216810..48217739)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (48386306..48387235)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (48238362..48239291)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene SEC61 translocon subunit beta pseudogene Neighboring gene Sharpr-MPRA regulatory region 14057 Neighboring gene Sharpr-MPRA regulatory region 4641 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:47968069-47969268 Neighboring gene Sharpr-MPRA regulatory region 13015 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:47995557-47996216 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:47996217-47996876 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3339 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3340 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:48015112-48015327 Neighboring gene GATA motif-containing MPRA enhancer 240 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4711 Neighboring gene protein tyrosine phosphatase receptor type J Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4712 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3341 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4713 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:48050132-48050706 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3342 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:48072419-48072920 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:48072921-48073420 Neighboring gene Sharpr-MPRA regulatory region 8111 Neighboring gene NANOG hESC enhancer GRCh37_chr11:48077877-48078378 Neighboring gene Sharpr-MPRA regulatory region 12058 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:48092882-48093057 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:48112153-48112964 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:48119178-48119678 Neighboring gene microRNA 3161 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:48149227-48149587 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:48198445-48198617 Neighboring gene NANOG hESC enhancer GRCh37_chr11:48212556-48213092 Neighboring gene olfactory receptor family 4 subfamily B member 2 pseudogene Neighboring gene olfactory receptor family 4 subfamily X member 2

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
olfactory receptor 4B1
Names
olfactory receptor OR11-106

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005470.1NP_001005470.1  olfactory receptor 4B1

    See identical proteins and their annotated locations for NP_001005470.1

    Status: PROVISIONAL

    Source sequence(s)
    AC026975
    Consensus CDS
    CCDS31485.1
    UniProtKB/Swiss-Prot
    Q6IF75, Q8NGF8, Q96R64
    UniProtKB/TrEMBL
    A0A126GVH6
    Related
    ENSP00000311605.2, ENST00000309562.3
    Conserved Domains (2) summary
    pfam00001
    Location:39285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29303
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    48216810..48217739
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    48386306..48387235
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)