OR52E2 olfactory receptor family 52 subfamily E member 2 [Homo sapiens (human)] - Gene

Summary

Official Symbol: OR52E2provided by HGNC
Official Full Name: olfactory receptor family 52 subfamily E member 2provided by HGNC
Primary source: HGNC:HGNC:14769
See related: Ensembl:ENSG00000176787 AllianceGenome:HGNC:14769
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 11p15.4

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	11	NC_000011.10 (5058650..5059627, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	11	NC_060935.1 (5115562..5116539, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	11	NC_000011.9 (5079880..5080857, complement)

Chromosome 11 - NC_000011.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

Go to the top of the page Help

Markers

ECD00811 (e-PCR)
- UniSTS:281920

REN96661 (e-PCR)
- UniSTS:421459

REN96662 (e-PCR)
- UniSTS:421460

ECD01864 (e-PCR)
- UniSTS:282965

REN96663 (e-PCR)
- UniSTS:421461

REN96664 (e-PCR)
- UniSTS:421462

REN96665 (e-PCR)
- UniSTS:421463

REN96666 (e-PCR)
- UniSTS:421464

REN96667 (e-PCR)
- UniSTS:421465

REN96668 (e-PCR)
- UniSTS:421466

REN96669 (e-PCR)
- UniSTS:421467

REN96670 (e-PCR)
- UniSTS:421468

REN96671 (e-PCR)
- UniSTS:421469

REN96672 (e-PCR)
- UniSTS:421470

REN96673 (e-PCR)
- UniSTS:421471

REN96674 (e-PCR)
- UniSTS:421472

ECD21982 (e-PCR)
- UniSTS:302973

REN96815 (e-PCR)
- UniSTS:421613

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in detection of chemical stimulus involved in sensory perception of smell	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: olfactory receptor 52E2

Names: olfactory receptor, family 10, subfamily AC, member 1 pseudogene

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005164.2 → NP_001005164.2 olfactory receptor 52E2

See identical proteins and their annotated locations for NP_001005164.2

Status: VALIDATED

Source sequence(s)

AC113331

Consensus CDS

CCDS31371.1

UniProtKB/Swiss-Prot

Q8NGJ4

UniProtKB/TrEMBL

A0A126GVI9

Related

ENSP00000322088.2, ENST00000321522.2

Conserved Domains (2) summary

pfam00001
Location:43 → 293

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:33 → 311

7tm_4; Olfactory receptor