U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Atp5g1 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9) [ Mus musculus (house mouse) ]

Gene ID: 11951, updated on 7-Aug-2022

Summary

Official Symbol
Atp5g1provided by MGI
Official Full Name
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)provided by MGI
Primary source
MGI:MGI:107653
See related
Ensembl:ENSMUSG00000006057 AllianceGenome:MGI:107653
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Atp5mc1
Summary
Predicted to enable ligand-gated channel activity. Predicted to be involved in several processes, including ATP synthesis coupled proton transport; cellular response to L-glutamate; and negative regulation of mitochondrial membrane potential. Predicted to act upstream of or within ion transport. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; liver; and nervous system. Orthologous to human ATP5MC1 (ATP synthase membrane subunit c locus 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in heart adult (RPKM 958.8), duodenum adult (RPKM 383.7) and 27 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Atp5g1 in Genome Data Viewer
Location:
11; 11 D
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (95963619..95966520, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (96072793..96075694, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (95934107..95937008, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) Neighboring gene ubiquitin-conjugating enzyme E2Z Neighboring gene predicted gene, 22423 Neighboring gene calcium binding and coiled-coil domain 2 Neighboring gene tubulin tyrosine ligase-like family, member 6

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ligand-gated channel activity ISO
Inferred from Sequence Orthology
more info
 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables proton transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in ATP biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in ATP metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to L-glutamate ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of mitochondrial membrane potential ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of reactive oxygen species biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in pore complex assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of axon extension ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of neuron death ISO
Inferred from Sequence Orthology
more info
 
involved_in proton motive force-driven ATP synthesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ATP synthase F(0) complex subunit C1, mitochondrial
Names
ATP synthase lipid-binding protein, mitochondrial
ATP synthase membrane subunit c locus 1
ATP synthase proteolipid P1
ATPase protein 9
ATPase subunit c

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001161419.1NP_001154891.1  ATP synthase F(0) complex subunit C1, mitochondrial

    See identical proteins and their annotated locations for NP_001154891.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate 5' UTR exon, as compared to variant 1.
    Source sequence(s)
    AK009883, BY276643, CF749235
    Consensus CDS
    CCDS25289.1
    UniProtKB/Swiss-Prot
    Q3TIE9, Q9CR84
    Related
    ENSMUSP00000103312.2, ENSMUST00000107684.2
    Conserved Domains (1) summary
    MTH00222
    Location:62136
    ATP9; ATP synthase F0 subunit 9; Provisional
  2. NM_007506.6NP_031532.2  ATP synthase F(0) complex subunit C1, mitochondrial

    See identical proteins and their annotated locations for NP_031532.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) and variant 2 encode the same protein.
    Source sequence(s)
    AK010868, BY297329, CF749235
    Consensus CDS
    CCDS25289.1
    UniProtKB/Swiss-Prot
    Q3TIE9, Q9CR84
    Related
    ENSMUSP00000088029.6, ENSMUST00000090541.12
    Conserved Domains (1) summary
    MTH00222
    Location:62136
    ATP9; ATP synthase F0 subunit 9; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    95963619..95966520 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245490.2XP_030101350.1  ATP synthase F(0) complex subunit C1, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    Q3TIE9
    Related
    ENSMUSP00000103314.2, ENSMUST00000107686.8
    Conserved Domains (1) summary
    MTH00222
    Location:62136
    ATP9; ATP synthase F0 subunit 9; Provisional